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Emmanuel Botzolakis
Emmanuel Botzolakis
Mecklenburg Radiology Associates
Verified email at meckrad.com
Title
Cited by
Cited by
Year
Artificial intelligence system approaching neuroradiologist-level differential diagnosis accuracy at brain MRI
AM Rauschecker, JD Rudie, L Xie, J Wang, MT Duong, EJ Botzolakis, ...
Radiology 295 (3), 626-637, 2020
1042020
Enhanced macroscopic desensitization shapes the response of α4 subtype‐containing GABAA receptors to synaptic and extrasynaptic GABA
AH Lagrange, EJ Botzolakis, RL Macdonald
The Journal of physiology 578 (3), 655-676, 2007
1012007
Relation of melatonin to sleep architecture in children with autism
RM Leu, L Beyderman, EJ Botzolakis, K Surdyka, L Wang, BA Malow
Journal of autism and developmental disorders 41, 427-433, 2011
932011
GABAA receptor α1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABAA …
L Ding, HJ Feng, RL Macdonald, EJ Botzolakis, N Hu, MJ Gallagher
Journal of biological chemistry 285 (34), 26390-26405, 2010
592010
Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of …
J Zhao, DS Matthies, EJ Botzolakis, RL Macdonald, RD Blakely, P Hedera
Journal of Neuroscience 28 (51), 13938-13951, 2008
532008
Benzodiazepine modulation of GABAA receptor opening frequency depends on activation context: A patch clamp and simulation study
MT Bianchi, EJ Botzolakis, AH Lagrange, RL Macdonald
Epilepsy research 85 (2-3), 212-220, 2009
512009
A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly
W Lo, EJ Botzolakis, X Tang, RL Macdonald
Journal of biological chemistry 283 (44), 29740-29752, 2008
502008
Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation
MT Bianchi, EJ Botzolakis, KF Haas, JL Fisher, RL Macdonald
The Journal of physiology 584 (3), 769-787, 2007
482007
Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?
MT Bianchi, EJ Botzolakis
BMC pharmacology 10, 1-8, 2010
402010
GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2 (R177G)
E Todd, KN Gurba, EJ Botzolakis, AK Stanic, RL Macdonald
Neurobiology of disease 69, 215-224, 2014
382014
The effect of HSP-causing mutations in SPG3A and NIPA1 on the assembly, trafficking, and interaction between atlastin-1 and NIPA1
EJ Botzolakis, J Zhao, KN Gurba, RL Macdonald, P Hedera
Molecular and Cellular Neuroscience 46 (1), 122-135, 2011
352011
Achieving synaptically relevant pulses of neurotransmitter using PDMS microfluidics
EJ Botzolakis, A Maheshwari, HJ Feng, AH Lagrange, JH Shaver, ...
Journal of neuroscience methods 177 (2), 294-302, 2009
312009
Comparison of γ-aminobutyric acid, type A (GABAA), receptor αβγ and αβδ expression using flow cytometry and electrophysiology: evidence for alternative subunit stoichiometries …
EJ Botzolakis, KN Gurba, AH Lagrange, HJ Feng, AK Stanic, N Hu, ...
Journal of Biological Chemistry 291 (39), 20440-20461, 2016
292016
Context-dependent modulation of αβγ and αβδ GABAA receptors by penicillin: Implications for phasic and tonic inhibition
HJ Feng, EJ Botzolakis, RL Macdonald
Neuropharmacology 56 (1), 161-173, 2009
212009
Subspecialty-level deep gray matter differential diagnoses with deep learning and Bayesian networks on clinical brain MRI: a pilot study
JD Rudie, AM Rauschecker, L Xie, J Wang, MT Duong, EJ Botzolakis, ...
Radiology: Artificial Intelligence 2 (5), e190146, 2020
192020
GABAA receptor channels
RL Macdonald, EJ Botzolakis
Physiology and Pathology of Chloride Transporters and Channels in the …, 2009
152009
Bayesian network interface for assisting radiology interpretation and education
J Duda, E Botzolakis, PH Chen, S Mohan, I Nasrallah, A Rauschecker, ...
Medical imaging 2018: imaging informatics for healthcare, research, and …, 2018
112018
Brain mri deep learning and bayesian inference system augments radiology resident performance
JD Rudie, J Duda, MT Duong, PH Chen, L Xie, R Kurtz, JB Ware, J Choi, ...
Journal of Digital Imaging 34 (4), 1049-1058, 2021
72021
Feasibility of streamlining an interactive Bayesian-based diagnostic support tool designed for clinical practice
PH Chen, E Botzolakis, S Mohan, RN Bryan, T Cook
Medical Imaging 2016: PACS and Imaging Informatics: Next Generation and …, 2016
72016
Comparison of-Aminobutyric Acid, Type A (GABAA), Receptor and Expression Using Flow Cytometry and Electrophysiology
EJ Botzolakis, KN Gurba, XAH Lagrange, HJ Feng, XAK Stanic, N Hu, ...
THE JOURNAL OF BIOLOGICAL CHEMISTRY 291 (39), 20440-20461, 2016
52016
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