Artificial intelligence system approaching neuroradiologist-level differential diagnosis accuracy at brain MRI AM Rauschecker, JD Rudie, L Xie, J Wang, MT Duong, EJ Botzolakis, ... Radiology 295 (3), 626-637, 2020 | 104 | 2020 |
Enhanced macroscopic desensitization shapes the response of α4 subtype‐containing GABAA receptors to synaptic and extrasynaptic GABA AH Lagrange, EJ Botzolakis, RL Macdonald The Journal of physiology 578 (3), 655-676, 2007 | 101 | 2007 |
Relation of melatonin to sleep architecture in children with autism RM Leu, L Beyderman, EJ Botzolakis, K Surdyka, L Wang, BA Malow Journal of autism and developmental disorders 41, 427-433, 2011 | 93 | 2011 |
GABAA receptor α1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABAA … L Ding, HJ Feng, RL Macdonald, EJ Botzolakis, N Hu, MJ Gallagher Journal of biological chemistry 285 (34), 26390-26405, 2010 | 59 | 2010 |
Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of … J Zhao, DS Matthies, EJ Botzolakis, RL Macdonald, RD Blakely, P Hedera Journal of Neuroscience 28 (51), 13938-13951, 2008 | 53 | 2008 |
Benzodiazepine modulation of GABAA receptor opening frequency depends on activation context: A patch clamp and simulation study MT Bianchi, EJ Botzolakis, AH Lagrange, RL Macdonald Epilepsy research 85 (2-3), 212-220, 2009 | 51 | 2009 |
A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly W Lo, EJ Botzolakis, X Tang, RL Macdonald Journal of biological chemistry 283 (44), 29740-29752, 2008 | 50 | 2008 |
Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation MT Bianchi, EJ Botzolakis, KF Haas, JL Fisher, RL Macdonald The Journal of physiology 584 (3), 769-787, 2007 | 48 | 2007 |
Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity? MT Bianchi, EJ Botzolakis BMC pharmacology 10, 1-8, 2010 | 40 | 2010 |
GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2 (R177G) E Todd, KN Gurba, EJ Botzolakis, AK Stanic, RL Macdonald Neurobiology of disease 69, 215-224, 2014 | 38 | 2014 |
The effect of HSP-causing mutations in SPG3A and NIPA1 on the assembly, trafficking, and interaction between atlastin-1 and NIPA1 EJ Botzolakis, J Zhao, KN Gurba, RL Macdonald, P Hedera Molecular and Cellular Neuroscience 46 (1), 122-135, 2011 | 35 | 2011 |
Achieving synaptically relevant pulses of neurotransmitter using PDMS microfluidics EJ Botzolakis, A Maheshwari, HJ Feng, AH Lagrange, JH Shaver, ... Journal of neuroscience methods 177 (2), 294-302, 2009 | 31 | 2009 |
Comparison of γ-aminobutyric acid, type A (GABAA), receptor αβγ and αβδ expression using flow cytometry and electrophysiology: evidence for alternative subunit stoichiometries … EJ Botzolakis, KN Gurba, AH Lagrange, HJ Feng, AK Stanic, N Hu, ... Journal of Biological Chemistry 291 (39), 20440-20461, 2016 | 29 | 2016 |
Context-dependent modulation of αβγ and αβδ GABAA receptors by penicillin: Implications for phasic and tonic inhibition HJ Feng, EJ Botzolakis, RL Macdonald Neuropharmacology 56 (1), 161-173, 2009 | 21 | 2009 |
Subspecialty-level deep gray matter differential diagnoses with deep learning and Bayesian networks on clinical brain MRI: a pilot study JD Rudie, AM Rauschecker, L Xie, J Wang, MT Duong, EJ Botzolakis, ... Radiology: Artificial Intelligence 2 (5), e190146, 2020 | 19 | 2020 |
GABAA receptor channels RL Macdonald, EJ Botzolakis Physiology and Pathology of Chloride Transporters and Channels in the …, 2009 | 15 | 2009 |
Bayesian network interface for assisting radiology interpretation and education J Duda, E Botzolakis, PH Chen, S Mohan, I Nasrallah, A Rauschecker, ... Medical imaging 2018: imaging informatics for healthcare, research, and …, 2018 | 11 | 2018 |
Brain mri deep learning and bayesian inference system augments radiology resident performance JD Rudie, J Duda, MT Duong, PH Chen, L Xie, R Kurtz, JB Ware, J Choi, ... Journal of Digital Imaging 34 (4), 1049-1058, 2021 | 7 | 2021 |
Feasibility of streamlining an interactive Bayesian-based diagnostic support tool designed for clinical practice PH Chen, E Botzolakis, S Mohan, RN Bryan, T Cook Medical Imaging 2016: PACS and Imaging Informatics: Next Generation and …, 2016 | 7 | 2016 |
Comparison of-Aminobutyric Acid, Type A (GABAA), Receptor and Expression Using Flow Cytometry and Electrophysiology EJ Botzolakis, KN Gurba, XAH Lagrange, HJ Feng, XAK Stanic, N Hu, ... THE JOURNAL OF BIOLOGICAL CHEMISTRY 291 (39), 20440-20461, 2016 | 5 | 2016 |