O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease NP Marotta, YH Lin, YE Lewis, MR Ambroso, BW Zaro, MT Roth, ... Nature chemistry 7 (11), 913-920, 2015 | 277 | 2015 |
Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein T Abeywardana, YH Lin, R Rott, S Engelender, MR Pratt Chemistry & biology 20 (10), 1207-1213, 2013 | 53 | 2013 |
Inhibiting the hexosamine biosynthetic pathway lowers O-GlcNAcylation levels and sensitizes cancer to environmental stress LA Walter, YH Lin, CJ Halbrook, KN Chuh, L He, NJ Pedowitz, AR Batt, ... Biochemistry 59 (34), 3169-3179, 2019 | 33 | 2019 |
Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein … YE Lewis, T Abeywardana, YH Lin, A Galesic, MR Pratt ACS chemical biology 11 (4), 931-942, 2016 | 32 | 2016 |
A Dual Small‐Molecule Rheostat for Precise Control of Protein Concentration in Mammalian Cells YH Lin, MR Pratt ChemBioChem 15 (6), 805-809, 2014 | 10 | 2014 |
O‑GlcNAc modification blocks the aggregation and toxicity of the protein α‑synuclein associated with Parkinson’s disease. Nat Chem. 2015; 7: 913–20 NP Marotta, YH Lin, YE Lewis, MR Ambroso, BW Zaro, MT Roth, ... | 7 | |
Probing hGFAT1 activity through small-molecule inhibition, CRISPR and Cryo-EM: Identifying the downstream effects of O-GlcNAc modified proteins and their role in cancer cell … L Walter, YH Lin, K Chuh, F Nasertorabi, R Stevens, M Pratt ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
Using Chemical Biology Approaches to Investigate the Consequences of Protein Concentration and Activity in Cancer Cells YH Lin University of Southern California, 2016 | | 2016 |