Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci PL De Jager, G Srivastava, K Lunnon, J Burgess, LC Schalkwyk, L Yu, ... Nature neuroscience 17 (9), 1156-1163, 2014 | 901 | 2014 |
The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ plaques CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ... Cell reports 27 (4), 1293-1306. e6, 2019 | 595 | 2019 |
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease K Lunnon, R Smith, E Hannon, PL De Jager, G Srivastava, M Volta, ... Nature neuroscience 17 (9), 1164-1170, 2014 | 549 | 2014 |
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes T Raj, K Rothamel, S Mostafavi, C Ye, MN Lee, JM Replogle, T Feng, ... Science 344 (6183), 519-523, 2014 | 534 | 2014 |
Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease L Yu, LB Chibnik, GP Srivastava, N Pochet, J Yang, J Xu, J Kozubek, ... JAMA neurology 72 (1), 15-24, 2015 | 280 | 2015 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 2020 | 207 | 2020 |
Epigenomics of Alzheimer’s disease DA Bennett, L Yu, J Yang, HU Klein, PL De Jager Translating Epigenetics to the Clinic, 227-278, 2017 | 138 | 2017 |
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex ASP Lim, GP Srivastava, L Yu, LB Chibnik, J Xu, AS Buchman, ... PLoS genetics 10 (11), e1004792, 2014 | 96 | 2014 |
Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing EJ Lee, L Pei, G Srivastava, T Joshi, G Kushwaha, JH Choi, ... Nucleic acids research 39 (19), e127-e127, 2011 | 79 | 2011 |
5′RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy DC Christodoulou, H Wakimoto, K Onoue, S Eminaga, JM Gorham, ... The Journal of clinical investigation 124 (3), 1364-1370, 2014 | 67 | 2014 |
Alzheimer's loci: epigenetic associations and interaction with genetic factors LB Chibnik, L Yu, ML Eaton, G Srivastava, JA Schneider, M Kellis, ... Annals of clinical and translational neurology 2 (6), 636-647, 2015 | 59 | 2015 |
Wingless directly represses DPP morphogen expression via an armadillo/TCF/Brinker complex H Theisen, A Syed, BT Nguyen, T Lukacsovich, J Purcell, GP Srivastava, ... PLoS One 2 (1), e142, 2007 | 59 | 2007 |
Harnessing peripheral DNA methylation differences in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease A Vasanthakumar, JW Davis, K Idler, JF Waring, E Asque, B Riley-Gillis, ... Clinical epigenetics 12, 1-11, 2020 | 52 | 2020 |
Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach BA Logsdon, TM Perumal, V Swarup, M Wang, C Funk, C Gaiteri, M Allen, ... BioRxiv, 510420, 2019 | 42 | 2019 |
A link between SIN1 (MAPKAP1) and poly (rC) binding protein 2 (PCBP2) in counteracting environmental stress D Ghosh, GP Srivastava, D Xu, LC Schulz, RM Roberts Proceedings of the National Academy of Sciences 105 (33), 11673-11678, 2008 | 40 | 2008 |
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults GT Valenca, GP Srivastava, J Oliveira-Filho, CC White, L Yu, ... PLoS One 11 (7), e0157452, 2016 | 34 | 2016 |
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies J Yang, L Yu, C Gaiteri, GP Srivastava, LB Chibnik, SE Leurgans, ... The international journal of biochemistry & cell biology 67, 58-64, 2015 | 33 | 2015 |
A 17q12 allele is associated with altered NK cell subsets and function Z Xia, Q Liu, CT Berger, BT Keenan, A Kaliszewska, PC Cheney, ... The Journal of Immunology 188 (7), 3315-3322, 2012 | 31 | 2012 |
PRIMEGENS-v2: genome-wide primer design for analyzing DNA methylation patterns of CpG islands GP Srivastava, J Guo, H Shi, D Xu Bioinformatics 24 (17), 1837-1842, 2008 | 28 | 2008 |
Homolog-specific PCR primer design for profiling splice variants GP Srivastava, M Hanumappa, G Kushwaha, HT Nguyen, D Xu Nucleic acids research 39 (10), e69-e69, 2011 | 25 | 2011 |