Stefano Persiani
Stefano Persiani
Director Translational Sciences and Pharmacokinetics
Email confirmado em rottapharmbiotech.com
TítuloCitado porAno
Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis
VB Kraus, B Burnett, J Coindreau, S Cottrell, D Eyre, M Gendreau, ...
Osteoarthritis and Cartilage 19 (5), 515-542, 2011
2372011
Glucosamine oral bioavailability and plasma pharmacokinetics after increasing doses of crystalline glucosamine sulfate in man
S Persiani, E Roda, LC Rovati, M Locatelli, G Giacovelli, A Roda
Osteoarthritis and cartilage 13 (12), 1041-1049, 2005
1872005
Synovial and plasma glucosamine concentrations in osteoarthritic patients following oral crystalline glucosamine sulphate at therapeutic dose
S Persiani, R Rotini, G Trisolino, LC Rovati, M Locatelli, D Paganini, ...
Osteoarthritis and Cartilage 15 (7), 764-772, 2007
1382007
Development and validation of a sensitive HPLC–ESI-MS/MS method for the direct determination of glucosamine in human plasma
A Roda, L Sabatini, A Barbieri, M Guardigli, M Locatelli, FS Violante, ...
Journal of Chromatography B 844 (1), 119-126, 2006
682006
Pharmacokinetics, pharmacodynamics, and tolerability of cabergoline, a prolactin-lowering drug, after administration of increasing oral doses (0.5, 1.0, and 1.5 milligrams) in …
AC Andreotti, E Pianezzola, S Persiani, MA Pacciarini, M Strolin Benedetti, ...
The Journal of Clinical Endocrinology & Metabolism 80 (3), 841-845, 1995
561995
Crystalline glucosamine sulfate in the management of knee osteoarthritis: efficacy, safety, and pharmacokinetic properties
LC Rovati, F Girolami, S Persiani
Therapeutic advances in musculoskeletal disease 4 (3), 167-180, 2012
542012
OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis
VB Kraus, FJ Blanco, M Englund, Y Henrotin, LS Lohmander, E Losina, ...
Osteoarthritis and cartilage 23 (5), 686-697, 2015
452015
Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers
G Fornasini, N Monti, G Brogin, M Gallina, M Eandi, S Persiani, M Bani, ...
Chirality 9 (3), 297-302, 1997
381997
Transcellular processing of disulfide‐and thioether‐linked peroxidase‐polylysine conjugates in cultured MDCK epithelial cells
J Wan, S Persiani, WC Shen
Journal of cellular physiology 145 (1), 9-15, 1990
311990
Polylysine conjugates of Bowman–Birk protease inhibitor as targeted anti-carcinogenic agents
S Persiani, A Yeung, WC Shen, AR Kennedy
Carcinogenesis 12 (6), 1149-1152, 1991
301991
Development and validation of a HPLC–ES-MS/MS method for the determination of glucosamine in human synovial fluid
E Pastorini, R Rotini, M Guardigli, S Vecchiotti, S Persiani, G Trisolino, ...
Journal of Pharmaceutical and Biomedical Analysis 50 (5), 1009-1014, 2009
292009
Determination of the new aromatase inhibitor exemestane in biological fluids by automated high-performance liquid chromatography followed by radioimmunoassay
S Persiani, F Broutin, P Cicioni, P Stefanini, MS Benedetti
European journal of pharmaceutical sciences 4 (6), 331-340, 1996
281996
Pharmacokinetics of oral fenretinide in neuroblastoma patients: indications for optimal dose and dosing schedule also with respect to the active metabolite 4-oxo-fenretinide
F Formelli, E Cavadini, R Luksch, A Garaventa, MG Villani, V Appierto, ...
Cancer chemotherapy and pharmacology 62 (4), 655-665, 2008
272008
Glucosamine sulfate inhibits IL-1-stimulated gene expression at concentrations found in humans after oral intake.
T Piepoli, T Zanelli, O Letari, S Persiani, LC Rovati, G Caselli
Arthritis and Rheumatism 52 (9), S502-S503, 2005
272005
A double‐blind, placebo‐controlled study to assess tolerability, pharmacokinetics and preliminary pharmacodynamics of single escalating doses of Z13752A, a novel dual inhibitor …
M Bani, A Colantoni, M Guillaume, F Macchi, G Moroni, S Persiani
British journal of clinical pharmacology 50 (4), 338-349, 2000
262000
Glucosamine plasma and synovial fluid concentrations before and after oral administration of crystalline glucosamine sulfate in knee osteoarthritis patients.
S Persiani, R Rotini, G Trisolino, L Delliponti, LC Rovati, M Locatelli, ...
ARTHRITIS AND RHEUMATISM 52 (9), S508-S508, 2005
242005
Pharmacodynamics and relative bioavailability of cabergoline tablets vs solution in healthy volunteers
S Persiani, G Sassolas, G Piscitelli, CA Bizollon, I Poggesi, E Pianezzola, ...
Journal of pharmaceutical sciences 83 (10), 1421-1424, 1994
221994
Clinical and pharmacokinetic evaluation of L-dopa and cabergoline cotreatment in Parkinson's disease.
PD Del, A Colzi, E Musatti, MB Strolin, S Persiani, R Fariello, U Bonuccelli
Clinical neuropharmacology 20 (5), 455-465, 1997
201997
Pharmacokinetics of andolast after administration of single escalating doses by inhalation in mild asthmatic patients
S Persiani, M D'Amato, F Makovec, SH Arshad, ST Holgate, LC Rovati
Biopharmaceutics & drug disposition 22 (2), 73-81, 2001
192001
Pharmacokinetics of dexloxiglumide after administration of single and repeat oral escalating doses in healthy young males.
S Persiani, M D'Amato, F Makovec, IA Tavares, PM Bishai, LC Rovati
International journal of clinical pharmacology and therapeutics 40 (5), 198-206, 2002
182002
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