Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors KA Schalper, M Carleton, M Zhou, T Chen, Y Feng, SP Huang, AM Walsh, ... Nature medicine 26 (5), 688-692, 2020 | 354 | 2020 |
Clinical validation of PBRM1 alterations as a marker of immune checkpoint inhibitor response in renal cell carcinoma DA Braun, Y Ishii, AM Walsh, EM Van Allen, CJ Wu, SA Shukla, ... JAMA oncology 5 (11), 1631-1633, 2019 | 193 | 2019 |
Cell patterning chip for controlling the stem cell microenvironment A Rosenthal, A Macdonald, J Voldman Biomaterials 28 (21), 3208-3216, 2007 | 192 | 2007 |
STK11 and KEAP1 mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort S Papillon-Cavanagh, P Doshi, R Dobrin, J Szustakowski, AM Walsh ESMO open 5 (2), e000706, 2020 | 167 | 2020 |
Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes R Ai, D Hammaker, DL Boyle, R Morgan, AM Walsh, S Fan, GS Firestein, ... Nature communications 7 (1), 11849, 2016 | 135 | 2016 |
Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression Y Guo, AM Walsh, M Canavan, MD Wechalekar, S Cole, X Yin, B Scott, ... PloS one 13 (2), e0192704, 2018 | 113 | 2018 |
Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus S Cole, A Walsh, X Yin, MD Wechalekar, MD Smith, SM Proudman, ... Arthritis research & therapy 20, 1-14, 2018 | 106 | 2018 |
CD40L-dependent pathway is active at various stages of rheumatoid arthritis disease progression Y Guo, AM Walsh, U Fearon, MD Smith, MD Wechalekar, X Yin, S Cole, ... The Journal of Immunology 198 (11), 4490-4501, 2017 | 99 | 2017 |
p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state S Senturk, Z Yao, M Camiolo, B Stiles, T Rathod, AM Walsh, ... Proceedings of the National Academy of Sciences 111 (32), E3287-E3296, 2014 | 93 | 2014 |
Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations AM Walsh, JW Whitaker, CC Huang, Y Cherkas, SL Lamberth, ... Genome biology 17, 1-16, 2016 | 78 | 2016 |
Kinetic model for lamellipodal actin-integrin'clutch'dynamics A Macdonald, AR Horwitz, DA Lauffenburger Cell adhesion & migration 2 (2), 95-105, 2008 | 45 | 2008 |
Triple DMARD treatment in early rheumatoid arthritis modulates synovial T cell activation and plasmablast/plasma cell differentiation pathways AM Walsh, MD Wechalekar, Y Guo, X Yin, H Weedon, SM Proudman, ... PLoS One 12 (9), e0183928, 2017 | 42 | 2017 |
Sprouty2 drives drug resistance and proliferation in glioblastoma AM Walsh, GS Kapoor, JM Buonato, LK Mathew, Y Bi, RV Davuluri, ... Molecular Cancer Research 13 (8), 1227-1237, 2015 | 39 | 2015 |
Regulation of EGFR trafficking and cell signaling by Sprouty2 and MIG6 in lung cancer cells AM Walsh, MJ Lazzara Journal of cell science 126 (19), 4339-4348, 2013 | 34 | 2013 |
Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis M Canavan, AM Walsh, V Bhargava, SM Wade, T McGarry, V Marzaioli, ... JCI insight 3 (23), 2018 | 32 | 2018 |
Integration of the transcriptome and genome-wide landscape of BRD2 and BRD4 binding motifs identifies key superenhancer genes and reveals the mechanism of bet inhibitor action … V Krishna, X Yin, Q Song, A Walsh, D Pocalyko, K Bachman, I Anderson, ... The Journal of Immunology 206 (2), 422-431, 2021 | 26 | 2021 |
Molecular correlates of response to nivolumab at baseline and on treatment in patients with RCC P Ross-Macdonald, AM Walsh, SD Chasalow, R Ammar, ... Journal for immunotherapy of cancer 9 (3), 2021 | 26 | 2021 |
Quantitative proteomic analysis of diabetes mellitus in heart failure with preserved ejection fraction TC Hanff, JB Cohen, L Zhao, A Javaheri, P Zamani, SB Prenner, ... Basic to Translational Science 6 (2), 89-99, 2021 | 21 | 2021 |
Plasma biomarkers associated with adverse outcomes in patients with calcific aortic stenosis MK Vidula, A Orlenko, L Zhao, L Salvador, AM Small, E Horton, JB Cohen, ... European Journal of Heart Failure 23 (12), 2021-2032, 2021 | 19 | 2021 |
Exploratory analysis of Janus kinase 1 (JAK1) loss-of-function (LoF) mutations in patients with DNA mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H … S Kopetz, T Andre, MJ Overman, V Zagonel, S Lonardi, M Aglietta, ... Cancer Research 78 (13_Supplement), 2603-2603, 2018 | 13 | 2018 |