Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2 … IV Magedov, M Manpadi, MA Ogasawara, AS Dhawan, S Rogelj, ... Journal of medicinal chemistry 51 (8), 2561-2570, 2008 | 180 | 2008 |
Discovery and investigation of antiproliferative and apoptosis-inducing properties of new heterocyclic podophyllotoxin analogues accessible by a one-step multicomponent synthesis IV Magedov, M Manpadi, S Van Slambrouck, WFA Steelant, E Rozhkova, ... Journal of medicinal chemistry 50 (21), 5183-5192, 2007 | 159 | 2007 |
Three-component synthesis and anticancer evaluation of polycyclic indenopyridines lead to the discovery of a novel indenoheterocycle with potent apoptosis inducing properties M Manpadi, PY Uglinskii, SK Rastogi, KM Cotter, YSC Wong, ... Organic & biomolecular chemistry 5 (23), 3865-3872, 2007 | 120 | 2007 |
C C Fragmentation: Origins and Recent Applications MA Drahl, M Manpadi, LJ Williams Angewandte Chemie International Edition 52 (43), 11222-11251, 2013 | 102 | 2013 |
Antiproliferative and apoptosis inducing properties of pyrano [3, 2-c] pyridones accessible by a one-step multicomponent synthesis IV Magedov, M Manpadi, NM Evdokimov, EM Elias, E Rozhkova, ... Bioorganic & medicinal chemistry letters 17 (14), 3872-3876, 2007 | 91 | 2007 |
Anticancer properties of an important drug lead podophyllotoxin can be efficiently mimicked by diverse heterocyclic scaffolds accessible via one-step synthesis IV Magedov, L Frolova, M Manpadi, U Bhoga, H Tang, NM Evdokimov, ... Journal of medicinal chemistry 54 (12), 4234-4246, 2011 | 66 | 2011 |
Novel three-component synthesis and antiproliferative properties of diversely functionalized pyrrolines IV Magedov, G Luchetti, NM Evdokimov, M Manpadi, WFA Steelant, ... Bioorganic & medicinal chemistry letters 18 (4), 1392-1396, 2008 | 65 | 2008 |
Allene Synthesis via C− C Fragmentation: Method and Mechanistic Insight RV Kolakowski, M Manpadi, Y Zhang, TJ Emge, LJ Williams Journal of the American Chemical Society 131 (36), 12910-12911, 2009 | 61 | 2009 |
Total syntheses of pancratistatin. A review M Manpadi, A Kornienko Organic preparations and procedures international 40 (2), 107-161, 2008 | 60 | 2008 |
Synthesis and Biological Evaluation of Aromatic Analogues of Conduritol F, l-chiro-Inositol, and Dihydroconduritol F Structurally Related to the Amaryllidaceae … AS Kireev, ON Nadein, VJ Agustin, NE Bush, A Evidente, M Manpadi, ... The Journal of Organic Chemistry 71 (15), 5694-5707, 2006 | 58 | 2006 |
Structural simplification of bioactive natural products with multicomponent synthesis: dihydropyridopyrazole analogues of podophyllotoxin IV Magedov, M Manpadi, E Rozhkova, NM Przheval’skii, S Rogelj, ... Bioorganic & medicinal chemistry letters 17 (5), 1381-1385, 2007 | 55 | 2007 |
Synthesis of structurally simplified analogues of pancratistatin: truncation of the cyclitol ring M Manpadi, AS Kireev, IV Magedov, J Altig, P Tongwa, MY Antipin, ... The Journal of organic chemistry 74 (18), 7122-7131, 2009 | 36 | 2009 |
Selectivity guidelines and a reductive elimination-based model for predicting the stereochemical course of conjugate addition reactions of organocuprates to γ-alkoxy-α, β-enoates AS Kireev, M Manpadi, A Kornienko The Journal of organic chemistry 71 (7), 2630-2640, 2006 | 35 | 2006 |
Van slambrouck IV Magedov, M Manpadi, MA Ogasawara, AS Dhawan, S Rogelj Steelant, WFA, 2561-2570, 2008 | 32 | 2008 |
S. Van slambrouck, WFA Steelant, E. Rozhkova, NM Przheval’skii, S. Rogelj, A. Kornienko IV Magedov, M Manpadi J. Med. Chem 50 (5183), e5192, 2007 | 30 | 2007 |
S. Van slambrouck, P. Tongwa, MY Antipin and A. Kornienko IV Magedov, G Luchetti, NM Evdokimov, M Manpadi, WFA Steelant Bioorg. Med. Chem. Lett 18, 1392, 2008 | 25 | 2008 |
Tin-free radical reactions under minimal solvent conditions for the synthesis of substituted chromones and coumarins JR Zimmerman, M Manpadi, R Spatney Green Chemistry 13 (11), 3103-3106, 2011 | 24 | 2011 |
C‐C‐Fragmentierung: Herkunft und jüngste Anwendungen MA Drahl, M Manpadi, LJ Williams Angewandte Chemie 125 (43), 11430-11461, 2013 | 23 | 2013 |
Highly anti-selective conjugate addition of arylcuprates to a γ-alkoxy-α, β-enoate. A new method to address stereochemical challenges presented by Amaryllidaceae alkaloids M Manpadi, A Kornienko Tetrahedron letters 46 (26), 4433-4437, 2005 | 22 | 2005 |
A two-step, single pot procedure for the synthesis of substituted dihydropyrazolo-pyrimidines JR Zimmerman, BJ Myers, S Bouhall, A McCarthy, O Johntony, ... Tetrahedron Letters 55 (4), 936-940, 2014 | 16 | 2014 |