Raphael Tze Chuen Lee
Raphael Tze Chuen Lee
Senior Research Officer, Bioinformatics Institute, A*STAR
Email confirmado em bii.a-star.edu.sg
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Characteristics of a widespread community cluster of H275Y oseltamivir-resistant A (H1N1) pdm09 influenza in Australia
AC Hurt, K Hardie, NJ Wilson, YM Deng, M Osbourn, SK Leang, RTC Lee, ...
The Journal of infectious diseases 206 (2), 148-157, 2012
1622012
The contrasting phylodynamics of human influenza B viruses
D Vijaykrishna, EC Holmes, U Joseph, M Fourment, YCF Su, R Halpin, ...
Elife 4, e05055, 2015
1242015
Increased detection in Australia and Singapore of a novel influenza A (H1N1) 2009 variant with reduced oseltamivir and zanamivir sensitivity due to a S247N neuraminidase mutation
AC Hurt, RT Lee, SK Leang, L Cui, YM Deng, SP Phuah, N Caldwell, ...
Eurosurveillance 16 (23), 19884, 2011
1222011
Mapping the sequence mutations of the 2009 H1N1 influenza A virus neuraminidase relative to drug and antibody binding sites
S Maurer-Stroh, J Ma, RTC Lee, FL Sirota, F Eisenhaber
Biology direct 4 (1), 1-9, 2009
1192009
Estimating the fitness advantage conferred by permissive neuraminidase mutations in recent oseltamivir-resistant A (H1N1) pdm09 influenza viruses
J Butler, KA Hooper, S Petrie, R Lee, S Maurer-Stroh, L Reh, ...
PLoS Pathog 10 (4), e1004065, 2014
1132014
Genetic alterations in the tyrosine kinase transcriptome of human cancer cell lines
JE Ruhe, S Streit, S Hart, CH Wong, K Specht, P Knyazev, T Knyazeva, ...
Cancer research 67 (23), 11368-11376, 2007
992007
A new common mutation in the hemagglutinin of the 2009 (H1N1) influenza A virus
S Maurer-Stroh, RTC Lee, F Eisenhaber, L Cui, SP Phuah, RTP Lin
PLoS Currents 2, 2010
912010
A new pandemic influenza A (H1N1) genetic variant predominated in the winter 2010 influenza season in Australia, New Zealand and Singapore
IG Barr, L Cui, N Komadina, RT Lee, RT Lin, Y Deng, N Caldwell, R Shaw, ...
Eurosurveillance 15 (42), 19692, 2010
872010
Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2014–2015
AC Hurt, TG Besselaar, RS Daniels, B Ermetal, A Fry, L Gubareva, ...
Antiviral research 132, 178-185, 2016
862016
Antigenic drift of the pandemic 2009 A (H1N1) influenza virus in A ferret model
T Guarnaccia, LA Carolan, S Maurer-Stroh, RTC Lee, E Job, PC Reading, ...
PLoS Pathog 9 (5), e1003354, 2013
752013
Influenza A (H5N8) virus similar to strain in Korea causing highly pathogenic avian influenza in Germany
T Harder, S Maurer-Stroh, A Pohlmann, E Starick, D Höreth-Böntgen, ...
Emerging infectious diseases 21 (5), 860, 2015
692015
Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors and status of novel antivirals, 2016–2017
A Lackenby, TG Besselaar, RS Daniels, A Fry, V Gregory, LV Gubareva, ...
Antiviral research 157, 38-46, 2018
612018
The highly pathogenic H7N3 avian influenza strain from July 2012 in Mexico acquired an extended cleavage site through recombination with host 28S rRNA
S Maurer-Stroh, RTC Lee, V Gunalan, F Eisenhaber
Virology journal 10 (1), 139, 2013
572013
Early transmission patterns of coronavirus disease 2019 (COVID-19) in travellers from Wuhan to Thailand, January 2020
P Okada, R Buathong, S Phuygun, T Thanadachakul, S Parnmen, ...
Eurosurveillance 25 (8), 2000097, 2020
512020
Emergence of oseltamivir-resistant pandemic (H1N1) 2009 virus within 48 hours
M Inoue, T Barkham, YS Leo, KP Chan, A Chow, CW Wong, RTC Lee, ...
Emerging infectious diseases 16 (10), 1633, 2010
482010
South-east Asian Zika virus strain linked to cluster of cases in Singapore, August 2016
S Maurer-Stroh, TM Mak, YK Ng, SP Phuah, RG Huber, JK Marzinek, ...
Eurosurveillance 21 (38), 30347, 2016
412016
BRCA1 and BRCA2 mutations in an Asian clinic-based population detected using a comprehensive strategy
P Ang, IHK Lim, TC Lee, JT Luo, DCT Ong, PH Tan, ASG Lee
Cancer Epidemiology and Prevention Biomarkers 16 (11), 2276-2284, 2007
322007
Influenza viruses with B/Yamagata-and B/Victoria-like neuraminidases are differentially affected by mutations that alter antiviral susceptibility
R Farrukee, SK Leang, J Butler, RTC Lee, S Maurer-Stroh, D Tilmanis, ...
Journal of Antimicrobial Chemotherapy 70 (7), 2004-2012, 2015
312015
F-BAR domain proteins: families and function
S Ahmed, W Bu, RTC Lee, S Maurer-Stroh, WI Goh
Communicative & integrative biology 3 (2), 116-121, 2010
312010
All that glitters is not gold-founder effects complicate associations of flu mutations to disease severity
RTC Lee, CLS Santos, TM de Paiva, L Cui, FL Sirota, F Eisenhaber, ...
Virology journal 7 (1), 297, 2010
282010
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