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Nam Chu
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Akt kinase activation mechanisms revealed using protein semisynthesis
N Chu, AL Salguero, AZ Liu, Z Chen, DR Dempsey, SB Ficarro, ...
Cell 174 (4), 897-907. e14, 2018
1062018
Enzyme-catalyzed expressed protein ligation
SH Henager, N Chu, Z Chen, D Bolduc, DR Dempsey, Y Hwang, J Wells, ...
Nature methods 13, 925-927, 2016
682016
Biophysical analysis of the interaction of Rab6a GTPase with its effector domains
T Bergbrede, N Chuky, S Schoebel, W Blankenfeldt, M Geyer, E Fuchs, ...
Journal of biological chemistry 284 (5), 2628-2635, 2009
622009
The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling
N Chu, T Viennet, H Bae, A Salguero, A Boeszoermenyi, H Arthanari, ...
Elife 9, e59151, 2020
482020
A C-terminal membrane anchor affects the interactions of prion proteins with lipid membranes
NK Chu, W Shabbir, E Bove-Fenderson, C Araman, R Lemmens-Gruber, ...
Journal of Biological Chemistry 289 (43), 30144-30160, 2014
352014
AKTivation mechanisms
PA Cole, N Chu, AL Salguero, H Bae
Current opinion in structural biology 59, 47-53, 2019
342019
Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics
E Akinci, M Cha, L Lin, G Yeo, MC Hamilton, CJ Donahue, ...
BioRxiv, 2020
252020
Honey bee odorant-binding protein 14: Effects on thermal stability upon odorant binding revealed by FT-IR spectroscopy and CD measurements
A Schwaighofer, C Kotlowski, C Araman, N Chu, R Mastrogiacomo, ...
European Biophysics Journal 43, 105-112, 2014
222014
Protein immobilization on liposomes and lipid‐coated nanoparticles by protein trans‐splicing
NK Chu, D Olschewski, R Seidel, KF Winklhofer, J Tatzelt, M Engelhard, ...
Journal of Peptide Science 16 (10), 582-588, 2010
222010
Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs
MS Taylor, DR Dempsey, Y Hwang, Z Chen, N Chu, JD Boeke, PA Cole
Bioorganic chemistry 62, 64-73, 2015
192015
The protein kinase Akt acts as a coat adaptor in endocytic recycling
JW Hsu, M Bai, K Li, JS Yang, N Chu, PA Cole, MJ Eck, J Li, VW Hsu
Nature cell biology 22 (8), 927-933, 2020
182020
Getting the most out of your crystals: Data collection at the new high-flux, microfocus MX beamlines at NSLS-II
MS Miller, S Maheshwari, W Shi, Y Gao, N Chu, AS Soares, PA Cole, ...
Molecules 24 (3), 496, 2019
162019
Semisynthesis of membrane‐attached prion proteins
NK Chu, CFW Becker
Methods in enzymology 462, 177-193, 2009
162009
Studying weak and dynamic interactions of posttranslationally modified proteins using expressed protein ligation
K Tripsianes, NK Chu, A Friberg, M Sattler, CFW Becker
ACS Chemical Biology 9 (2), 347-352, 2014
132014
Recombinant expression of soluble murine prion protein for C-terminal modification
NK Chu, CFW Becker
FEBS letters 587 (5), 430-435, 2013
102013
PH domain-mediated autoinhibition and oncogenic activation of Akt
H Bae, T Viennet, E Park, N Chu, A Salguero, MJ Eck, H Arthanari, ...
Elife 11, e80148, 2022
82022
Multifaceted regulation of Akt by diverse C-terminal post-translational modifications
AL Salguero, M Chen, AT Balana, N Chu, H Jiang, BA Palanski, H Bae, ...
ACS chemical biology 17 (1), 68-76, 2021
82021
Utilizing a baculovirus/insect cell expression system and expressed protein ligation (EPL) for protein semisynthesis
M Butts, N Chu
Current protocols 2 (1), e348, 2022
32022
Protein Semisynthesis
N Chu, PA Cole
Total Chemical Synthesis of Proteins, 307-326, 2021
12021
Switching immune signals on and off
N Chu, PA Cole
Elife 4, e07204, 2015
12015
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