Victor W Pike
Victor W Pike
Chief of PET Radiopharmaceutical Sciences
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Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers
J Hirvonen, RS Goodwin, CT Li, GE Terry, SS Zoghbi, C Morse, VW Pike, ...
Molecular psychiatry 17 (6), 642-649, 2012
PET radiotracers: crossing the blood–brain barrier and surviving metabolism
VW Pike
Trends in pharmacological sciences 30 (8), 431-440, 2009
Chemistry with [18F]Fluoride Ion
L Cai, S Lu, VW Pike
European Journal of Organic Chemistry 2008 (17), 2853-2873, 2008
Mixed-affinity binding in humans with 18-kDa translocator protein ligands
DRJ Owen, RN Gunn, EA Rabiner, I Bennacef, M Fujita, WC Kreisl, ...
Journal of nuclear medicine 52 (1), 24-32, 2011
In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease
WC Kreisl, CH Lyoo, M McGwier, J Snow, KJ Jenko, N Kimura, W Corona, ...
Brain 136 (7), 2228-2238, 2013
Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H] WAY-100635 and [11C] way-100635
H Hall, C Lundkvist, C Halldin, L Farde, VW Pike, JA McCarron, A Fletcher, ...
Brain research 745 (1-2), 96-108, 1997
Tracer kinetic modeling of the 5-HT1AReceptor ligand [carbonyl-11C] WAY-100635 for PET
RN Gunn, PA Sargent, CJ Bench, EA Rabiner, S Osman, VW Pike, ...
Neuroimage 8 (4), 426-440, 1998
Comparison of [11C]-(R)-PK 11195 and [11C] PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: implications for positron emission tomographic imaging …
WC Kreisl, M Fujita, Y Fujimura, N Kimura, KJ Jenko, P Kannan, J Hong, ...
Neuroimage 49 (4), 2924-2932, 2010
Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C] WAY-100635
VW Pike, JA McCarron, AA Lammertsma, S Osman, SP Hume, ...
European journal of pharmacology 301 (1-3), R5-R7, 1996
A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of …
WC Kreisl, KJ Jenko, CS Hines, CH Lyoo, W Corona, CL Morse, ...
Journal of Cerebral Blood Flow & Metabolism 33 (1), 53-58, 2013
Recommendations for a practical production of [11C]methyl iodide
C Crouzel, B Langström, VW Pike, HH Coenen
Applied radiation and isotopes 38 (8), 601-603, 1987
Synthesis of the enantiomers of [N-methyl-11C] PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats
F Shah, SP Hume, VW Pike, S Ashworth, J McDermott
Nuclear medicine and biology 21 (4), 573-581, 1994
Cerebellum can serve as a pseudo-reference region in Alzheimer disease to detect neuroinflammation measured with PET radioligand binding to translocator protein
CH Lyoo, M Ikawa, JS Liow, SS Zoghbi, CL Morse, VW Pike, M Fujita, ...
Journal of Nuclear Medicine 56 (5), 701-706, 2015
Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation
M Fujita, M Imaizumi, SS Zoghbi, Y Fujimura, AG Farris, T Suhara, J Hong, ...
Neuroimage 40 (1), 43-52, 2008
Recommendations for fluorine-18 production
M Guillaume, A Luxen, B Nebeling, M Argentini, JC Clark, VW Pike
International journal of radiation applications and instrumentation. Part A …, 1991
Consensus nomenclature rules for radiopharmaceutical chemistry—Setting the record straight
HH Coenen, AD Gee, M Adam, G Antoni, CS Cutler, Y Fujibayashi, ...
Nuclear medicine and biology 55, v-xi, 2017
PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements
SS Zoghbi, HU Shetty, M Ichise, M Fujita, M Imaizumi, JS Liow, J Shah, ...
Journal of Nuclear Medicine 47 (3), 520-527, 2006
Synthesis and Evaluation in Monkey of Two Sensitive 11C-Labeled Aryloxyanilide Ligands for Imaging Brain Peripheral Benzodiazepine Receptors In Vivo
E Briard, SS Zoghbi, M Imaizumi, JP Gourley, HU Shetty, J Hong, ...
Journal of medicinal chemistry 51 (1), 17-30, 2008
Reactions of cyclotron-produced [18F] fluoride with diaryliodonium salts—a novel single-step route to no-carrier-added [18] fluoroarenes
VW Pike, FI Aigbirhio
Journal of the Chemical Society, Chemical Communications, 2215-2216, 1995
The “specific” P-glycoprotein inhibitor tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2)
P Kannan, S Telu, S Shukla, SV Ambudkar, VW Pike, C Halldin, ...
ACS chemical neuroscience 2 (2), 82-89, 2011
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