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Daniel Berwick
Daniel Berwick
Email confirmado em open.ac.uk
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The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes
DC Berwick, I Hers, KJ Heesom, SK Moule, JM Tavareá
Journal of Biological Chemistry 277 (37), 33895-33900, 2002
4642002
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles
DC Berwick, GC Dell, GI Welsh, KJ Heesom, I Hers, LM Fletcher, ...
Journal of cell science 117 (25), 5985-5993, 2004
1852004
A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation
BMH Law, VA Spain, VHL Leinster, R Chia, A Beilina, HJ Cho, ...
Journal of Biological Chemistry 289 (2), 895-908, 2014
1682014
Role of protein kinase B in insulin-regulated glucose uptake
GI Welsh, I Hers, DC Berwick, G Dell, M Wherlock, R Birkin, S Leney, ...
Biochemical Society Transactions 33 (2), 346-349, 2005
1622005
The importance of Wnt signalling for neurodegeneration in Parkinson's disease
DC Berwick, K Harvey
Biochemical Society Transactions 40 (5), 1123-1128, 2012
1512012
LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same
DC Berwick, GR Heaton, S Azeggagh, K Harvey
Molecular Neurodegeneration 14, 1-22, 2019
1342019
LRRK2 signaling pathways: the key to unlocking neurodegeneration?
DC Berwick, K Harvey
Trends in cell biology 21 (5), 257-265, 2011
1172011
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
DC Berwick, K Harvey
Human molecular genetics 21 (22), 4966-4979, 2012
1162012
The regulation and deregulation of Wnt signaling by PARK genes in health and disease
DC Berwick, K Harvey
Journal of molecular cell biology 6 (1), 3-12, 2014
792014
Identifying protein kinase substrates: hunting for the organ-grinder's monkeys
DC Berwick, JM Tavaré
Trends in biochemical sciences 29 (5), 227-232, 2004
762004
Protective LRRK2 R1398H variant enhances GTPase and Wnt signaling activity
J Nixon-Abell, DC Berwick, S Grannó, VA Spain, C Blackstone, K Harvey
Frontiers in molecular neuroscience 9, 18, 2016
752016
Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling
DC Berwick, B Javaheri, A Wetzel, M Hopkinson, J Nixon-Abell, S Grannò, ...
Molecular neurodegeneration 12, 1-17, 2017
672017
The relevance of α-KLOTHO to the central nervous system: some key questions
MM Cararo-Lopes, CHY Mazucanti, C Scavone, EM Kawamoto, ...
Ageing research reviews 36, 137-148, 2017
632017
LRRK2: an éminence grise of Wnt-mediated neurogenesis?
DC Berwick, K Harvey
Frontiers in cellular neuroscience 7, 82, 2013
432013
The development of inhibitors of leucine‐rich repeat kinase 2 (LRRK2) as a therapeutic strategy for Parkinson's disease: the current state of play
S Azeggagh, DC Berwick
British journal of pharmacology 179 (8), 1478-1495, 2022
412022
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus
S Granno, J Nixon-Abell, DC Berwick, J Tosh, G Heaton, S Almudimeegh, ...
Scientific reports 9 (1), 7322, 2019
292019
L'RRK de Triomphe: a solution for LRRK2 GTPase activity?
J Nixon-Abell, DC Berwick, K Harvey
Biochemical Society Transactions 44 (6), 1625-1634, 2016
202016
A simple technique for the prediction of interacting proteins reveals a direct Brn-3a-androgen receptor interaction
DC Berwick, JKJ Diss, VS Budhram-Mahadeo, DS Latchman
Journal of biological chemistry 285 (20), 15286-15295, 2010
202010
Regulation Of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation
DC Berwick, M Calissano, JD Corness, SJ Cook, DS Latchman
Brain research 1256, 8-18, 2009
122009
Building Bridges In Neuropharmacology: New therapeutic approaches for psychiatric and neurodegenerative disorders
A Bailey, DC Berwick, R Camarini, C Scavone
British Journal of Pharmacology 179 (8), 1475-1477, 2022
22022
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Artigos 1–20