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Michelle L. Block
Michelle L. Block
Indiana University School of Medicine, Department of Anatomy & Cell Biology. The Stark Neuroscience
Email confirmado em iupui.edu - Página inicial
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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
ML Block, L Zecca, JS Hong
Nature Reviews Neuroscience 8 (1), 57-69, 2007
45702007
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
L Qin, X Wu, ML Block, Y Liu, GR Breese, JS Hong, DJ Knapp, FT Crews
Glia 55 (5), 453-462, 2007
23472007
Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism
ML Block, JS Hong
Progress in neurobiology 76 (2), 77-98, 2005
18532005
Air pollution: mechanisms of neuroinflammation and CNS disease
ML Block, L Calderón-Garcidueñas
Trends in neurosciences 32 (9), 506-516, 2009
14852009
Aggregated α‐synuclein activates microglia: a process leading to disease progression in Parkinson's disease
W Zhang, T Wang, Z Pei, DS Miller, X Wu, ML Block, B Wilson, W Zhang, ...
The FASEB Journal 19 (6), 533-542, 2005
14012005
Microglial activation and chronic neurodegeneration
ME Lull, ML Block
Neurotherapeutics 7 (4), 354-365, 2010
10492010
NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia
L Qin, Y Liu, T Wang, SJ Wei, ML Block, B Wilson, B Liu, JS Hong
Journal of Biological Chemistry 279 (2), 1415-1421, 2004
6872004
The outdoor air pollution and brain health workshop
ML Block, A Elder, RL Auten, SD Bilbo, H Chen, JC Chen, ...
Neurotoxicology 33 (5), 972-984, 2012
5442012
Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase
ML Block, X Wu, Z Pei, G Li, T Wang, L Qin, B Wilson, J Yang, JS Hong, ...
The FASEB journal 18 (13), 1618-1620, 2004
4322004
Chronic microglial activation and progressive dopaminergic neurotoxicity
ML Block, JS Hong
Biochemical Society Transactions 35 (5), 1127-1132, 2007
4062007
Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity
S Levesque, T Taetzsch, ME Lull, U Kodavanti, K Stadler, A Wagner, ...
Environmental health perspectives 119 (8), 1149-1155, 2011
3822011
Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease
S Levesque, MJ Surace, J McDonald, ML Block
Journal of neuroinflammation 8, 1-10, 2011
3642011
Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons
X Wu, PS Chen, S Dallas, B Wilson, ML Block, CC Wang, H Kinyamu, ...
International Journal of Neuropsychopharmacology 11 (8), 1123-1134, 2008
3342008
Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults
L Calderón-Garcidueñas, M Kavanaugh, M Block, A D'Angiulli, ...
Journal of Alzheimer's disease 28 (1), 93-107, 2012
2862012
Retinoic acid attenuates β-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model
Y Ding, A Qiao, Z Wang, JS Goodwin, ES Lee, ML Block, M Allsbrook, ...
Journal of Neuroscience 28 (45), 11622-11634, 2008
2852008
Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier
AMS Hartz, B Bauer, ML Block, JS Hong, DS Miller
The FASEB Journal 22 (8), 2723, 2008
2852008
A pivotal role of matrix metalloproteinase‐3 activity in dopaminergic neuronal degeneration via microglial activation
YS Kim, DH Choi, ML Block, S Lorenzl, L Yang, YJ Kim, S Sugama, ...
The FASEB Journal 21 (1), 179-187, 2007
2412007
Interactive role of the toll‐like receptor 4 and reactive oxygen species in LPS‐induced microglia activation
L Qin, G Li, X Qian, Y Liu, X Wu, B Liu, JS Hong, ML Block
Glia 52 (1), 78-84, 2005
2282005
NADPH oxidase as a therapeutic target in Alzheimer's disease
ML Block
BMC neuroscience 9 (Suppl 2), S8, 2008
2262008
Particulate matter, oxidative stress and neurotoxicity
SMJ MohanKumar, A Campbell, M Block, B Veronesi
Neurotoxicology 29 (3), 479-488, 2008
2152008
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Artigos 1–20