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David Blum
David Blum
Inserm UMR-S1172
Email confirmado em inserm.fr - Página inicial
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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease
D Blum, S Torch, N Lambeng, MF Nissou, AL Benabid, R Sadoul, ...
Progress in neurobiology 65 (2), 135-172, 2001
16022001
NLRP3 inflammasome activation drives tau pathology
C Ising, C Venegas, S Zhang, H Scheiblich, SV Schmidt, A Vieira-Saecker, ...
Nature 575 (7784), 669-673, 2019
9262019
3‐Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
E Brouillet, C Jacquard, N Bizat, D Blum
Journal of neurochemistry 95 (6), 1521-1540, 2005
4052005
Biochemistry of Tau in Alzheimer’s disease and related neurological disorders
N Sergeant, A Bretteville, M Hamdane, ML Caillet-Boudin, P Grognet, ...
Expert review of proteomics 5 (2), 207-224, 2008
3322008
Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?
C Laurent, L Buée, D Blum
Biomedical journal 41 (1), 21-33, 2018
3162018
Tau phosphorylation and sevoflurane anesthesia: an association to postoperative cognitive impairment
H Le Freche, J Brouillette, FJ Fernandez-Gomez, P Patin, R Caillierez, ...
The Journal of the American Society of Anesthesiologists 116 (4), 779-787, 2012
2792012
Targeting phospho-Ser422 by active Tau Immunotherapy in the THYTau22 mouse model: a suitable therapeutic approach
L Troquier, R Caillierez, S Burnouf, F J Fernandez-Gomez, ME Grosjean, ...
Current Alzheimer Research 9 (4), 397-405, 2012
2312012
Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy
C Laurent, G Dorothée, S Hunot, E Martin, Y Monnet, M Duchamp, ...
Brain 140 (1), 184-200, 2017
2162017
Novel Alzheimer risk genes determine the microglia response to amyloid‐β but not to TAU pathology
A Sierksma, A Lu, R Mancuso, N Fattorelli, N Thrupp, E Salta, J Zoco, ...
EMBO molecular medicine 12 (3), e10606, 2020
2142020
Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1–42 oligomers are revealed in vivo by using a novel animal model
J Brouillette, R Caillierez, N Zommer, C Alves-Pires, I Benilova, D Blum, ...
Journal of Neuroscience 32 (23), 7852-7861, 2012
2142012
Beneficial effects of caffeine in a transgenic model of Alzheimer's disease-like tau pathology
C Laurent, S Eddarkaoui, M Derisbourg, A Leboucher, D Demeyer, ...
Neurobiology of aging 35 (9), 2079-2090, 2014
2012014
Tau deletion promotes brain insulin resistance
E Marciniak, A Leboucher, E Caron, T Ahmed, A Tailleux, J Dumont, ...
Journal of Experimental Medicine 214 (8), 2257-2269, 2017
1942017
Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology
K Belarbi, S Burnouf, FJ Fernandez-Gomez, C Laurent, S Lestavel, ...
Neurobiology of disease 43 (2), 486-494, 2011
1942011
Clinical potential of minocycline for neurodegenerative disorders
D Blum, A Chtarto, L Tenenbaum, J Brotchi, M Levivier
Neurobiology of disease 17 (3), 359-366, 2004
1942004
Atypical, non-standard functions of the microtubule associated Tau protein
I Sotiropoulos, MC Galas, JM Silva, E Skoulakis, S Wegmann, MB Maina, ...
Acta neuropathologica communications 5, 1-11, 2017
1882017
Extracellular toxicity of 6-hydroxydopamine on PC12 cells
D Blum, S Torch, MF Nissou, AL Benabid, JM Verna
Neuroscience letters 283 (3), 193-196, 2000
1782000
A2A adenosine receptor deletion is protective in a mouse model of Tauopathy
C Laurent, S Burnouf, B Ferry, VL Batalha, JE Coelho, Y Baqi, E Malik, ...
Molecular psychiatry 21 (1), 97-107, 2016
1732016
Adenosine receptors and Huntington's disease: implications for pathogenesis and therapeutics
D Blum, R Hourez, MC Galas, P Popoli, SN Schiffmann
The Lancet Neurology 2 (6), 366-374, 2003
1642003
Premature ovarian aging in mice deficient for Gpr3
C Ledent, I Demeestere, D Blum, J Petermans, T Hämäläinen, G Smits, ...
Proceedings of the National Academy of Sciences 102 (25), 8922-8926, 2005
1582005
Altered neuronal excitability in cerebellar granule cells of mice lacking calretinin
D Gall, C Roussel, I Susa, E D'Angelo, P Rossi, B Bearzatto, MC Galas, ...
Journal of Neuroscience 23 (28), 9320-9327, 2003
1582003
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