Benjamin Cossins
Benjamin Cossins
Principal Scientist, UCB Celltech
Verified email at
Cited by
Cited by
Raman study of mechanically induced oxygenation state transition of red blood cells using optical tweezers
S Rao, Š Bálint, B Cossins, V Guallar, D Petrov
Biophysical journal 96 (1), 209-216, 2009
Understanding cryptic pocket formation in protein targets by enhanced sampling simulations
V Oleinikovas, G Saladino, BP Cossins, FL Gervasio
Journal of the American Chemical Society 138 (43), 14257-14263, 2016
Exploring hierarchical refinement techniques for induced fit docking with protein and ligand flexibility
KW Borrelli, B Cossins, V Guallar
Journal of computational chemistry 31 (6), 1224-1235, 2010
Exploring transition pathway and free-energy profile of large-scale protein conformational change by combining normal mode analysis and umbrella sampling molecular dynamics
J Wang, Q Shao, Z Xu, Y Liu, Z Yang, BP Cossins, H Jiang, K Chen, J Shi, ...
The Journal of Physical Chemistry B 118 (1), 134-143, 2014
Human immunoglobulin E flexes between acutely bent and extended conformations
N Drinkwater, BP Cossins, AH Keeble, M Wright, K Cain, H Hailu, ...
Nature structural & molecular biology 21 (4), 397-404, 2014
A new view of the bacterial cytosol environment
BP Cossins, MP Jacobson, V Guallar
PLoS Comput Biol 7 (6), e1002066, 2011
Exploration of protein conformational change with PELE and meta-dynamics
BP Cossins, A Hosseini, V Guallar
Journal of Chemical Theory and Computation 8 (3), 959-965, 2012
Force fields and scoring functions for carbohydrate simulation
X Xiong, Z Chen, BP Cossins, Z Xu, Q Shao, K Ding, W Zhu, J Shi
Carbohydrate research 401, 73-81, 2015
Allosteric mechanism of action of the therapeutic anti-IgE antibody omalizumab
AM Davies, EG Allan, AH Keeble, J Delgado, BP Cossins, AN Mitropoulou, ...
Journal of Biological Chemistry 292 (24), 9975-9987, 2017
Assessment of nonequilibrium free energy methods
BP Cossins, S Foucher, CM Edge, JW Essex
The Journal of Physical Chemistry B 113 (16), 5508-5519, 2009
Thermodynamics calculation of protein–ligand interactions by QM/MM polarizable charge parameters
J Wang, Q Shao, BP Cossins, J Shi, K Chen, W Zhu
Journal of Biomolecular Structure and Dynamics 34 (1), 163-176, 2016
Correlated inter-domain motions in adenylate kinase
S Esteban-Martín, RB Fenwick, J Ĺdén, B Cossins, CW Bertoncini, ...
PLoS Comput Biol 10 (7), e1003721, 2014
Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR
D Stöppler, A Macpherson, S Smith-Penzel, N Basse, F Lecomte, ...
PLoS biology 16 (5), e2006192, 2018
Mapping central α-Helix linker mediated conformational transition pathway of calmodulin via simple computational approach
J Wang, S Peng, BP Cossins, X Liao, K Chen, Q Shao, X Zhu, J Shi, ...
The Journal of Physical Chemistry B 118 (32), 9677-9685, 2014
Direct observation of single DNA structural alterations at low forces with surface-enhanced Raman scattering
S Rao, S Raj, B Cossins, M Marro, V Guallar, D Petrov
Biophysical journal 104 (1), 156-162, 2013
Small molecule targeting of protein–protein interactions through allosteric modulation of dynamics
BP Cossins, ADG Lawson
Molecules 20 (9), 16435-16445, 2015
Quantifying secondary structure changes in calmodulin using 2D-IR spectroscopy
L Minnes, DJ Shaw, BP Cossins, PM Donaldson, GM Greetham, M Towrie, ...
Analytical chemistry 89 (20), 10898-10906, 2017
Protein− Ligand Binding Affinity by Nonequilibrium Free Energy Methods
BP Cossins, S Foucher, CM Edge, JW Essex
The Journal of Physical Chemistry B 112 (47), 14985-14992, 2008
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer
J O’Connell, J Porter, B Kroeplien, T Norman, S Rapecki, R Davis, ...
Nature communications 10 (1), 1-12, 2019
Raman study of mechanically indued oxygenation state transition of red blood cells using optical tweezers.(vol 96, pg 209, 2009)
S Rao, S Balint, B Cossins, V Guallar, D Petrov
Biophysical Journal 96 (5), 2043-2043, 2009
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