Tumor targeting with a selective gelatinase inhibitor E Koivunen, W Arap, H Valtanen, A Rainisalo, OP Medina, P Heikkilä, ... Nature biotechnology 17 (8), 768-774, 1999 | 741 | 1999 |
Multimodal silica nanoparticles are effective cancer-targeted probes in a model of human melanoma M Benezra, O Penate-Medina, PB Zanzonico, D Schaer, H Ow, A Burns, ... The Journal of clinical investigation 121 (7), 2768-2780, 2011 | 726 | 2011 |
Clinical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe E Phillips, O Penate-Medina, PB Zanzonico, RD Carvajal, P Mohan, Y Ye, ... Science translational medicine 6 (260), 260ra149-260ra149, 2014 | 708 | 2014 |
Fluorescent silica nanoparticles with efficient urinary excretion for nanomedicine AA Burns, J Vider, H Ow, E Herz, O Penate-Medina, M Baumgart, ... Nano letters 9 (1), 442-448, 2009 | 497 | 2009 |
Targeted liposomal drug delivery in cancer OP Medina, Y Zhu, K Kairemo Current pharmaceutical design 10 (24), 2981-2989, 2004 | 261 | 2004 |
Liposomes and inorganic nanoparticles for drug delivery and cancer imaging C Heneweer, SEM Gendy, O Peñate-Medina Therapeutic delivery 3 (5), 645-656, 2012 | 101 | 2012 |
Fluorescent silica-based nanoparticles M Bradbury, U Wiesner, OP Medina, H Ow, A Burns, J Lewis, S Larson US Patent 9,625,456, 2017 | 89 | 2017 |
Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide OP Medina, K Kairemo, H Valtanen, A Kangasniemi, S Kaukinen, ... Anticancer research 25 (1A), 33-42, 2005 | 84 | 2005 |
Binding of Novel Peptide Inhibitors of Type IV Collagenases to Phospholipid Membranes and Use in Liposome Targeting to Tumor Cells in Vitro OP Medina, T Söderlund, LJ Laakkonen, EKJ Tuominen, E Koivunen, ... Cancer Research 61 (10), 3978-3985, 2001 | 75 | 2001 |
X-ray-based techniques to study the nano–bio interface C Sanchez-Cano, RA Alvarez-Puebla, JM Abendroth, T Beck, R Blick, ... ACS nano 15 (3), 3754-3807, 2021 | 72 | 2021 |
Sphingomyelinase activity associated with human plasma low density lipoprotein: possible functional implications JM Holopainen, OP Medina, AJ Metso, PKJ Kinnunen Journal of Biological Chemistry 275 (22), 16484-16489, 2000 | 68 | 2000 |
Optimizing tumor targeting of the lipophilic EGFR-binding radiotracer SKI 243 using a liposomal nanoparticle delivery system OP Medina, N Pillarsetty, A Glekas, B Punzalan, V Longo, M Gönen, ... Journal of controlled release 149 (3), 292-298, 2011 | 44 | 2011 |
Fluorine-labeled dasatinib nanoformulations as targeted molecular imaging probes in a PDGFB-driven murine glioblastoma model M Benezra, D Hambardzumyan, O Penate-Medina, DR Veach, ... Neoplasia 14 (12), 1132-IN8, 2012 | 42 | 2012 |
Liposomal tumor targeting in drug delivery utilizing MMP-2-and MMP-9-binding ligands O Penate Medina, M Haikola, M Tahtinen, I Simpura, S Kaukinen, ... Journal of drug delivery 2011, 2011 | 42 | 2011 |
Melanocortin-1 receptor-targeting ultrasmall silica nanoparticles for dual-modality human melanoma imaging F Chen, X Zhang, K Ma, B Madajewski, M Benezra, L Zhang, E Phillips, ... ACS applied materials & interfaces 10 (5), 4379-4393, 2018 | 41 | 2018 |
Multimodal silica-based nanoparticles MS Bradbury, U Wiesner, OP Medina, A Burns, JS Lewis, SM Larson US Patent 9,999,694, 2018 | 36 | 2018 |
Binding of cationic liposomes to apoptotic cells S Bose, I Tuunainen, M Parry, OP Medina, G Mancini, PKJ Kinnunen Analytical biochemistry 331 (2), 385-394, 2004 | 30 | 2004 |
Alpha-MSH Targeted Liposomal Nanoparticle for Imaging in Inflammatory Bowel Disease (IBD) T Peñate-Medina, C Damoah, M Benezra, O Will, K Kairemo, J Humbert, ... Current Pharmaceutical Design 26 (31), 3840-3846, 2020 | 14 | 2020 |
Selective gelatinase inhibitor peptide is effective in targeting tongue carcinoma cell tumors in vivo J Suojanen, ST Vilen, P Nyberg, P Heikkilä, O Penate-Medina, PEJ Saris, ... Anticancer Research 31 (11), 3659-3664, 2011 | 14 | 2011 |
Lipid-iron nanoparticle with a cell stress release mechanism combined with a local alternating magnetic field enables site-activated drug release T Peñate Medina, M Gerle, J Humbert, H Chu, AL Köpnick, R Barkmann, ... Cancers 12 (12), 3767, 2020 | 13 | 2020 |