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Darshita Budhadev
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Glycan-gold nanoparticles as multifunctional probes for multivalent lectin–carbohydrate binding: implications for blocking virus infection and nanoparticle assembly
D Budhadev, E Poole, I Nehlmeier, Y Liu, J Hooper, E Kalverda, ...
Journal of the American Chemical Society 142 (42), 18022-18034, 2020
632020
Site-selective C–C modification of proteins at neutral pH using organocatalyst-mediated cross aldol ligations
RJ Spears, RL Brabham, D Budhadev, T Keenan, S McKenna, J Walton, ...
Chemical Science 9 (25), 5585-5593, 2018
452018
Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands
SJ Richards, T Keenan, JB Vendeville, DE Wheatley, H Chidwick, ...
Chemical science 12 (3), 905-910, 2021
282021
Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors
D Budhadev, K Saxby, J Walton, G Davies, PC Tyler, R Schwörer, ...
Organic & biomolecular chemistry 17 (7), 1817-1821, 2019
222019
Development of a cell permeable red-shifted CHEF-based chemosensor for Al3+ ion by controlling PET
M Mukherjee, B Sen, S Pal, A Maji, D Budhadev, P Chattopadhyay
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 157, 11-16, 2016
152016
Biocatalytic transfer of pseudaminic acid (Pse5Ac7Ac) using promiscuous sialyltransferases in a chemoenzymatic approach to Pse5Ac7Ac-containing glycosides
EKP Flack, HS Chidwick, G Guchhait, T Keenan, D Budhadev, K Huang, ...
ACS Catalysis 10 (17), 9986-9993, 2020
112020
The characterisation of a galactokinase from Streptomyces coelicolor
T Keenan, R Mills, E Pocock, D Budhadev, F Parmeggiani, S Flitsch, ...
Carbohydrate research 472, 132-137, 2019
112019
Synthesis of two trisaccharides related to the hepatoprotective phenylethanoids leonoside E and F isolated from Leonurus japonicus Houtt
D Budhadev, B Mukhopadhyay
Carbohydrate research 384, 51-55, 2014
112014
Polyvalent Glycan Quantum Dots as a Multifunctional Tool for Revealing Thermodynamic, Kinetic, and Structural Details of Multivalent Lectin–Glycan Interactions
J Hooper, Y Liu, D Budhadev, DF Ainaga, N Hondow, D Zhou, Y Guo
ACS applied materials & interfaces 14 (42), 47385-47396, 2022
92022
Chemical synthesis of a tetrasaccharide related to the exocellular polysaccharide from Rhodococcus sp. RHA1
D Budhadev, B Mukhopadhyay
Carbohydrate research 394, 26-31, 2014
92014
Chemical synthesis of the pentasaccharide related to the repeating unit of the O-antigen of Enterobacter cloacae G2277
D Budhadev, B Mukhopadhyay
Tetrahedron 71 (36), 6155-6163, 2015
72015
Polyvalent Glycan Functionalized Quantum Nanorods as Mechanistic Probes for Shape-Selective Multivalent Lectin-Glycan Recognition
J Hooper, D Budhadev, DL Fernandez Ainaga, N Hondow, D Zhou, Y Guo
ACS Applied Nano Materials 6 (6), 4201-4213, 2023
62023
Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein
D Budhadev, J Hooper, C Rocha, I Nehlmeier, AM Kempf, M Hoffmann, ...
JACS Au 3 (6), 1755-1766, 2023
52023
Convergent synthesis of the hexasaccharide related to the repeating unit of the O-antigen from E. coli O120
D Budhadev, B Mukhopadhyay
RSC advances 5 (119), 98033-98040, 2015
42015
Probing Scaffold Size Effects on Multivalent Lectin-Glycan Binding Affinity, Thermodynamics and Antiviral Potency Using Polyvalent Glycan-Gold Nanoparticles
R Basaran, D Budhadev, A Kempf, I Nehlmeier, N Hondow, S Pöhlmann, ...
12024
The Retaining Pse5Ac7Ac Pseudaminyltransferase KpsS1 Defines a Previously Unreported glycosyltransferase family (GT118)
AJ Walklett, EKP Flack, HS Chidwick, NE Hatton, T Keenan, D Budhadev, ...
Angewandte Chemie, e202318523, 2024
12024
The retaining Pse5Ac7Ac pseudaminyltransferase KpsS1 defines a new glycosyltransferase family (GTXXX)
A Walklett, E Flack, H Chidwick, N Hatton, T Keenan, D Budhadev, ...
12023
Bioconjugation of polypeptides
MA Fascione, RJ Spears, R Brabham, D Budhadev, T Keenan
US Patent 11,897,917, 2024
2024
Polyvalent Glycomimetic-Gold Nanoparticle Conjugates reveal effects of glycan display on Multivalent Lectin-Glycan Interactions
X Ning, D Budhadev, S Pollastri, I Nehlmeier, A Kempf, I Manfield, ...
2024
Probing the pH-dependency of DC-SIGN/R multivalent lectin–glycan interactions using polyvalent glycan-gold nanoparticles
R Basaran, X Ning, D Budhadev, N Hondow, Y Guo, D Zhou
Nanoscale Advances, 2024
2024
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