Human C. hivin. 1 inhibitor: primary structure, cDNA cloning, and chromosomal localization SC Bock, K Skriver, E Nielsen, HC Thøgersen, B Wiman, VH Donaldson, ... Biochemistry 25 (15), 4292-4301, 1986 | 420 | 1986 |
A rapid and efficient one-tube PCR-based mutagenesis technique using Pfu DNA polymerase V Picard, E Ersdal-Badju, A Lu, SC Bock Nucleic acids research 22 (13), 2587-2591, 1994 | 311 | 1994 |
The sequence of human serum albumin cDNA and its expression in E. coli RM Lawn, J Adelman, SC Bock, AE Franke, CM Houck, R Najarian, ... Nucleic acids research 9 (22), 6103-6114, 1981 | 310 | 1981 |
Cloning and expression of the cDNA for human antithrom, bin III SC Bock, LL Wion, GA Vehar, RM Lawn Nucleic acids research 10 (24), 8113-8125, 1982 | 249 | 1982 |
Substrate properties of C1 inhibitor Ma (alanine 434----glutamic acid). Genetic and structural evidence suggesting that the P12-region contains critical determinants of serine … K Skriver, WR Wikoff, PA Patston, F Tausk, M Schapira, AP Kaplan, ... Journal of Biological Chemistry 266 (14), 9216-9221, 1991 | 164 | 1991 |
Assignment of the human antithrombin III structural gene to chromosome 1q23–25 SC Bock, JF Harris, I Balazs, JM Trent Cytogenetic and Genome Research 39 (1), 67-69, 1985 | 164 | 1985 |
Idealization of the hydrophobic segment of the alkaline phosphatase signal peptide DA Kendall, SC Bock, ET Kaiser Nature 321 (6071), 706-708, 1986 | 128 | 1986 |
Identification of the antithrombin III heparin binding site E Ersdal-Badju, A Lu, Y Zuo, V Picard, SC Bock Journal of Biological Chemistry 272 (31), 19393-19400, 1997 | 124 | 1997 |
The oligosaccharide side chain on Asn-135 of α-antithrombin, absent in β-antithrombin, decreases the heparin affinity of the inhibitor by affecting the heparin-induced … B Turk, I Brieditis, SC Bock, ST Olson, I Björk Biochemistry 36 (22), 6682-6691, 1997 | 124 | 1997 |
Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for … V Picard, E Ersdal-Badju, SC Bock Biochemistry 34 (26), 8433-8440, 1995 | 111 | 1995 |
Pleiotropic effects of antithrombin strand 1C substitution mutations. DA Lane, RJ Olds, J Conard, M Boisclair, SC Bock, M Hultin, ... Journal of Clinical Investigation 90 (6), 2422, 1992 | 106 | 1992 |
CpG mutations in the reactive site of human C1 inhibitor. K Skriver, E Radziejewska, JA Silbermann, VH Donaldson, SC Bock Journal of Biological Chemistry 264 (6), 3066-3071, 1989 | 106 | 1989 |
Antithrombin III Utah: proline-407 to leucine mutation in a highly conserved region near the inhibitor reactive site SC Bock, JA Marrinan, E Radziejewska Biochemistry 27 (16), 6171-6178, 1988 | 103 | 1988 |
Characterization of an unusual DNA length polymorphism 5'to the human antithrombin III gene SC Bock, DJ Levitan Nucleic acids research 11 (24), 8569-8582, 1983 | 94 | 1983 |
Intron structure of the human antithrombin III gene differs from that of other members of the serine protease inhibitor superfamily. EV Prochownik, SC Bock, SH Orkin Journal of Biological Chemistry 260 (17), 9608-9612, 1985 | 91 | 1985 |
Human apolipoprotein B cDNA clone isolation and demonstration that liver apolipoprotein B mRNA is 22 kilobases in length LS Huang, SC Bock, SI Feinstein, JL Breslow Proceedings of the National Academy of Sciences 82 (20), 6825, 1985 | 86 | 1985 |
Lysine 114 of antithrombin is of crucial importance for the affinity and kinetics of heparin pentasaccharide binding V Arocas, SC Bock, S Raja, ST Olson, I Björk Journal of Biological Chemistry 276 (47), 43809-43817, 2001 | 80 | 2001 |
Identification of critical molecular interactions mediating heparin activation of antithrombin: implications for the design of improved heparin anticoagulants ST Olson, I Björk, SC Bock Trends in cardiovascular medicine 12 (5), 198-205, 2002 | 77 | 2002 |
Role of arginine 129 in heparin binding and activation of antithrombin U Desai, R Swanson, SC Bock, I Björk, ST Olson Journal of Biological Chemistry 275 (25), 18976-18984, 2000 | 75 | 2000 |
Antithrombin Budapest 3 An antithrombin variant with reduced heparin affinity resulting from the substitution L99F RJ Olds, DA Lane, M Boisclair, G Sas, SC Bock, SL Thein FEBS letters 300 (3), 241-246, 1992 | 68 | 1992 |