| Primaquine revisited six decades after its discovery N Vale, R Moreira, P Gomes European journal of medicinal chemistry 44 (3), 937-953, 2009 | 425 | 2009 |
| Praziquantel for schistosomiasis: single-drug metabolism revisited, mode of action, and resistance N Vale, MJ Gouveia, G Rinaldi, PJ Brindley, F Gärtner, ... Antimicrobial agents and chemotherapy 61 (5), 10.1128/aac. 02582-16, 2017 | 338 | 2017 |
| Phenolic profiling of Portuguese propolis by LC–MS spectrometry: Uncommon propolis rich in flavonoid glycosides SI Falcão, N Vale, P Gomes, MRM Domingues, C Freire, SM Cardoso, ... Phytochemical Analysis 24 (4), 309-318, 2013 | 246 | 2013 |
| Combination of cell-penetrating peptides with nanoparticles for therapeutic application: a review S Silva, AJ Almeida, N Vale Biomolecules 9 (1), 22, 2019 | 204 | 2019 |
| “Recycling” classical drugs for malaria C Teixeira, N Vale, B Perez, A Gomes, JRB Gomes, P Gomes Chemical reviews 114 (22), 11164-11220, 2014 | 142 | 2014 |
| Antimicrobial peptides: a new class of antimalarial drugs? N Vale, L Aguiar, P Gomes Frontiers in Pharmacology 5, 125211, 2014 | 112 | 2014 |
| Imidazolidin-4-one derivatives of primaquine as novel transmission-blocking antimalarials MJ Araújo, J Bom, R Capela, C Casimiro, P Chambel, P Gomes, J Iley, ... Journal of medicinal chemistry 48 (3), 888-892, 2005 | 100 | 2005 |
| Phenolic quantification and botanical origin of Portuguese propolis SI Falcão, A Tomás, N Vale, P Gomes, C Freire, M Vilas-Boas Industrial Crops and Products 49, 805-812, 2013 | 96 | 2013 |
| In vitro evaluation of Portuguese propolis and floral sources for antiprotozoal, antibacterial and antifungal activity SI Falcão, N Vale, P Cos, P Gomes, C Freire, L Maes, M Vilas‐Boas Phytotherapy research 28 (3), 437-443, 2014 | 95 | 2014 |
| Tryptophan metabolism in depression: a narrative review with a focus on serotonin and kynurenine pathways AS Correia, N Vale International journal of molecular sciences 23 (15), 8493, 2022 | 86 | 2022 |
| Synthesis of imidazolidin-4-one and 1H-imidazo [2, 1-a] isoindole-2, 5 (3H, 9bH)-dione derivatives of primaquine: scope and limitations P Gomes, MJ Araújo, M Rodrigues, N Vale, Z Azevedo, J Iley, P Chambel, ... Tetrahedron 60 (26), 5551-5562, 2004 | 82 | 2004 |
| Cyclization-activated prodrugs P Gomes, N Vale, R Moreira Molecules 12 (11), 2484-2506, 2007 | 79 | 2007 |
| Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model MJ Gouveia, MY Pakharukova, T Laha, B Sripa, GA Maksimova, G Rinaldi, ... Carcinogenesis 38 (9), 929-937, 2017 | 75 | 2017 |
| Amino acids in the development of prodrugs N Vale, A Ferreira, J Matos, P Fresco, MJ Gouveia Molecules 23 (9), 2318, 2018 | 71 | 2018 |
| Tethering antimicrobial peptides onto chitosan: Optimization of azide-alkyne “click” reaction conditions M Barbosa, N Vale, FMTA Costa, MCL Martins, P Gomes Carbohydrate polymers 165, 384-393, 2017 | 70 | 2017 |
| Mass spectrometry techniques in the survey of steroid metabolites as potential disease biomarkers: a review MJ Gouveia, PJ Brindley, LL Santos, JMC da Costa, P Gomes, N Vale Metabolism 62 (9), 1206-1217, 2013 | 70 | 2013 |
| Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity AS Correia, A Cardoso, N Vale Antioxidants 12 (2), 470, 2023 | 68 | 2023 |
| Hydrogel depots for local co-delivery of osteoinductive peptides and mesenchymal stem cells FR Maia, M Barbosa, DB Gomes, N Vale, P Gomes, PL Granja, ... Journal of Controlled Release 189, 158-168, 2014 | 68 | 2014 |
| Snake venom peptides and low mass proteins: molecular tools and therapeutic agents JR Almeida, LM Resende, RK Watanabe, VC Carregari, ... Current medicinal chemistry 24 (30), 3254-3282, 2017 | 67 | 2017 |
| Evaluation of synergism in drug combinations and reference models for future orientations in oncology D Duarte, N Vale Current Research in Pharmacology and Drug Discovery 3, 100110, 2022 | 66 | 2022 |
