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Kathryn M Hart
Kathryn M Hart
Verified email at williams.edu - Homepage
Title
Cited by
Cited by
Year
Discovery of multiple hidden allosteric sites by combining Markov state models and experiments
GR Bowman, ER Bolin, KM Hart, BC Maguire, S Marqusee
Proceedings of the National Academy of Sciences 112 (9), 2734-2739, 2015
2002015
Modelling proteins' hidden conformations to predict antibiotic resistance
KM Hart, CMW Ho, S Dutta, ML Gross, GR Bowman
Nature Communications 7, 12965, 2016
1282016
Cleavable hydrophilic linker for one-bead-one-compound sequencing of oligomer libraries by tandem mass spectrometry
MG Paulick, KM Hart, KM Brinner, M Tjandra, DH Charych, ...
Journal of combinatorial chemistry 8 (3), 417-426, 2006
1082006
Thermodynamic system drift in protein evolution
KM Hart, MJ Harms, BH Schmidt, C Elya, JW Thornton, S Marqusee
PLoS biology 12 (11), e1001994, 2014
962014
Prediction of New Stabilizing Mutations Based on Mechanistic Insights from Markov State Models
MI Zimmerman, KM Hart, CA Sibbald, TE Frederick, JR Jimah, ...
ACS central science 3 (12), 1311-1321, 2017
672017
Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators
KM Hart, KE Moeder, CMW Ho, MI Zimmerman, TE Frederick, ...
PloS one 12 (6), e0178678, 2017
602017
Cooperative changes in solvent exposure identify cryptic pockets, switches, and allosteric coupling
JR Porter, KE Moeder, CA Sibbald, MI Zimmerman, KM Hart, ...
Biophysical journal 116 (5), 818-830, 2019
532019
Evolutionary trend toward kinetic stability in the folding trajectory of RNases H
SA Lim, KM Hart, MJ Harms, S Marqusee
Proceedings of the National Academy of Sciences 113 (46), 13045-13050, 2016
402016
BioBuilder: Synthetic biology in the lab
N Kuldell, R Bernstein, K Ingram, KM Hart
O'Reilly, 2015
35*2015
Tabtoxinine-β-lactam is a “stealth” β-lactam antibiotic that evades β-lactamase-mediated antibiotic resistance
KM Hart, M Reck, GR Bowman, TA Wencewicz
MedChemComm 7 (1), 118-127, 2016
152016
BioBuilder: Synthetic biology in the lab
R Bernstein, K Ingram, KM Hart
" O'Reilly Media, Inc.", 2015
62015
Natural and Synthetic Suppressor Mutations Defy Stability–Activity Tradeoffs
S Lee, CN Okoye, D Biesbrock, EC Harris, KF Miyasaki, RG Rilinger, ...
Biochemistry 61 (5), 398-407, 2022
22022
Differential effects of disulfide bond formation in TEM‐1 versus CTX‐M‐9 β‐lactamase
M Villanueva, LE Vostal, DN Cohen, D Biesbrock, EP Kuwaye, SG Driver, ...
Protein Science 33 (1), e4816, 2024
12024
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