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Nuno A. Fonseca
Nuno A. Fonseca
Center for Neuroscience and Cell Biology, University of Coimbra, Portugal
Email confirmado em cnc.uc.pt
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Ano
Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges
LC Gomes-da-Silva, NA Fonseca, V Moura, MC Pedroso de Lima, ...
Accounts of chemical research 45 (7), 1163-1171, 2012
2542012
Antibacterial activity of chitosan nanofiber meshes with liposomes immobilized releasing gentamicin
N Monteiro, M Martins, A Martins, NA Fonseca, JN Moreira, RL Reis, ...
Acta biomaterialia 18, 196-205, 2015
1822015
Current challenges and emerging opportunities of CAR-T cell therapies
TR Abreu, NA Fonseca, N Gonçalves, JN Moreira
Journal of Controlled Release 319, 246-261, 2020
1082020
Instructive nanofibrous scaffold comprising runt-related transcription factor 2 gene delivery for bone tissue engineering
N Monteiro, D Ribeiro, A Martins, S Faria, NA Fonseca, JN Moreira, ...
Acs Nano 8 (8), 8082-8094, 2014
972014
Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination
NA Fonseca, AS Rodrigues, P Rodrigues-Santos, V Alves, AC Gregório, ...
Biomaterials 69, 76-88, 2015
822015
Immobilization of bioactive factor-loaded liposomes on the surface of electrospun nanofibers targeting tissue engineering
N Monteiro, A Martins, R Pires, S Faria, NA Fonseca, JN Moreira, RL Reis, ...
Biomaterials science 2 (9), 1195-1209, 2014
652014
Nucleolin-based targeting strategies for cancer therapy: from targeted drug delivery to cytotoxic ligands
S Romano, N Fonseca, S Simoes, J Goncalves, JN Moreira
Drug Discovery Today 24 (10), 1985-2001, 2019
592019
Bridging cancer biology and the patients' needs with nanotechnology-based approaches
NA Fonseca, AC Gregorio, A Valerio-Fernandes, S Simoes, JN Moreira
Cancer Treatment Reviews 40 (5), 626-635, 2014
592014
Inoculated cell density as a determinant factor of the growth dynamics and metastatic efficiency of a breast cancer murine model
AC Gregorio, NA Fonseca, V Moura, M Lacerda, P Figueiredo, S Simoes, ...
PLoS One 11 (11), e0165817, 2016
482016
On the use of dexamethasone‐loaded liposomes to induce the osteogenic differentiation of human mesenchymal stem cells
N Monteiro, A Martins, D Ribeiro, S Faria, NA Fonseca, JN Moreira, ...
Journal of Tissue Engineering and Regenerative Medicine 9 (9), 1056-1066, 2015
462015
Simultaneous active intracellular delivery of doxorubicin and C6-ceramide shifts the additive/antagonistic drug interaction of non-encapsulated combination
NA Fonseca, LC Gomes-da-Silva, V Moura, S Simoes, JN Moreira
Journal of controlled release 196, 122-131, 2014
442014
Cancer stem cells and nucleolin as drivers of carcinogenesis
LS Carvalho, N Gonçalves, NA Fonseca, JN Moreira
Pharmaceuticals 14 (1), 60, 2021
402021
The cancer stem cell phenotype as a determinant factor of the heterotypic nature of breast tumors
NA Fonseca, AF Cruz, V Moura, S Simoes, JN Moreira
Critical reviews in oncology/hematology 113, 111-121, 2017
352017
Cell surface Nucleolin represents a novel cellular target for neuroblastoma therapy
C Brignole, V Bensa, NA Fonseca, G Del Zotto, S Bruno, AF Cruz, ...
Journal of Experimental & Clinical Cancer Research 40 (1), 180, 2021
312021
New integrative computational approaches unveil the Saccharomyces cerevisiae pheno-metabolomic fermentative profile and allow strain selection for winemaking
R Franco-Duarte, L Umek, I Mendes, CC Castro, N Fonseca, R Martins, ...
Food Chemistry 211, 509-520, 2016
282016
GMP-grade nanoparticle targeted to nucleolin downregulates tumor molecular signature, blocking growth and invasion, at low systemic exposure
NA Fonseca, AC Gregório, VM Mendes, R Lopes, T Abreu, N Gonçalves, ...
Nano Today 37, 101095, 2021
152021
The enhanced efficacy of intracellular delivery of doxorubicin/C6-ceramide combination mediated by the F3 peptide/nucleolin system is supported by the downregulation of the …
AF Cruz, MB Caleiras, NA Fonseca, N Goncalves, VM Mendes, ...
Cancers 13 (12), 3052, 2021
82021
Targeting cancer stem cells and non-stem cancer cells: The potential of lipid-based nanoparticles
AF Cruz, NA Fonseca, V Moura, S Simoes, JN Moreira
Current Pharmaceutical Design 23 (43), 6563-6572, 2017
82017
Platform for targeted delivery to stem cells and tumor cells and uses thereof
NAC da Fonseca, LCG Da Silva, VLDNC De, SPDM Simões, ...
US Patent App. 14/784,247, 2016
82016
Nucleolin overexpression predicts patient prognosis while providing a framework for targeted therapeutic intervention in lung cancer
 Valério-Fernandes, NA Fonseca, N Gonçalves, AF Cruz, MI Pereira, ...
Cancers 14 (9), 2217, 2022
72022
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