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Bryan J. Heard
Bryan J. Heard
University of Calgary, Faculty of Medicine
Email confirmado em ucalgary.ca
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Single intra‐articular dexamethasone injection immediately post‐surgery in a rabbit model mitigates early inflammatory responses and post‐traumatic osteoarthritis‐like alterations
BJ Heard, KI Barton, M Chung, Y Achari, NG Shrive, CB Frank, DA Hart
Journal of Orthopaedic Research 33 (12), 1826-1834, 2015
882015
Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid
BJ Heard, L Martin, JB Rattner, CB Frank, DA Hart, R Krawetz
BMC musculoskeletal disorders 13, 1-12, 2012
732012
Metabolic profiling of synovial fluid in a unilateral ovine model of anterior cruciate ligament reconstruction of the knee suggests biomarkers for early osteoarthritis
B Mickiewicz, BJ Heard, JK Chau, M Chung, DA Hart, NG Shrive, ...
Journal of Orthopaedic Research 33 (1), 71-77, 2015
702015
Monocyte chemotactic protein-1 inhibits chondrogenesis of synovial mesenchymal progenitor cells: an in vitro study
Q Harris, J Seto, K O'Brien, PS Lee, C Kondo, BJ Heard, DA Hart, ...
Stem Cells 31 (10), 2253-2265, 2013
672013
Changes of early post-traumatic osteoarthritis in an ovine model of simulated ACL reconstruction are associated with transient acute post-injury synovial inflammation and …
BJ Heard, NM Solbak, Y Achari, M Chung, DA Hart, NG Shrive, CB Frank
Osteoarthritis and Cartilage 21 (12), 1942-1949, 2013
532013
Complete ACL/MCL deficiency induces variable degrees of instability in sheep with specific kinematic abnormalities correlating with degrees of early osteoarthritis
CB Frank, JE Beveridge, KD Huebner, BJ Heard, JE Tapper, EJO O'Brien, ...
Journal of Orthopaedic Research 30 (3), 384-392, 2012
532012
Intraarticular and systemic inflammatory profiles may identify patients with osteoarthritis
BJ Heard, MJ Fritzler, JP Wiley, J McAllister, L Martin, H El-Gabalawy, ...
The Journal of rheumatology 40 (8), 1379-1387, 2013
482013
Early joint tissue changes are highly correlated with a set of inflammatory and degradative synovial biomarkers after ACL autograft and its sham surgery in an ovine model
BJ Heard, Y Achari, M Chung, NG Shrive, CB Frank
Journal of Orthopaedic Research 29 (8), 1185-1192, 2011
472011
A computational method to differentiate normal individuals, osteoarthritis and rheumatoid arthritis patients using serum biomarkers
BJ Heard, JM Rosvold, MJ Fritzler, H El-Gabalawy, JP Wiley, RJ Krawetz
Journal of The Royal Society Interface 11 (97), 20140428, 2014
452014
Ovine synovial membrane-derived mesenchymal progenitor cells retain the phenotype of the original tissue that was exposed to in-vivo inflammation: evidence for a suppressed …
W Ando, BJ Heard, M Chung, N Nakamura, CB Frank, DA Hart
Inflammation Research 61, 599-608, 2012
422012
Use of pre‐clinical surgically induced models to understand biomechanical and biological consequences of PTOA development
KI Barton, M Shekarforoush, BJ Heard, JL Sevick, P Vakil, M Atarod, ...
Journal of Orthopaedic Research 35 (3), 454-465, 2017
392017
Investigating the potential value of individual parameters of histological grading systems in a sheep model of cartilage damage: the Modified Mankin method
HR Moody, BJ Heard, CB Frank, NG Shrive, AO Oloyede
Journal of anatomy 221 (1), 47-54, 2012
382012
Osteoarthritis develops in the operated joint of an ovine model following ACL reconstruction with immediate anatomic reattachment of the native ACL
EJO O'Brien, JE Beveridge, KD Huebner, BJ Heard, JE Tapper, NG Shrive, ...
Journal of Orthopaedic Research 31 (1), 35-43, 2013
342013
Tibiofemoral centroid velocity correlates more consistently with cartilage damage than does contact path length in two ovine models of stifle injury
JE Beveridge, BJ Heard, NG Shrive, CB Frank
Journal of Orthopaedic Research 31 (11), 1745-1756, 2013
322013
The infrapatellar fat pad is affected by injury induced inflammation in the rabbit knee: use of dexamethasone to mitigate damage
BJ Heard, NM Solbak, M Chung, Y Achari, NG Shrive, CB Frank, DA Hart
Inflammation Research 65, 459-470, 2016
242016
Alterations in Hoffa’s fat pad induced by an inflammatory response following idealized anterior cruciate ligament surgery
NM Solbak, BJ Heard, Y Achari, M Chung, NG Shrive, CB Frank, DA Hart
Inflammation Research 64, 615-626, 2015
232015
Posttraumatic osteoarthritis development and progression in an ovine model of partial anterior cruciate ligament transection and effect of repeated intra-articular …
KI Barton, BJ Heard, JL Sevick, CR Martin, SMM Shekarforoush, M Chung, ...
The American Journal of Sports Medicine 46 (7), 1596-1605, 2018
222018
A new measure of tibiofemoral subchondral bone interactions that correlates with early cartilage damage in injured sheep
JE Beveridge, BJ Heard, JJY Brown, NG Shrive, CB Frank
Journal of Orthopaedic Research 32 (10), 1371-1380, 2014
152014
Diet-induced obesity leads to pro-inflammatory alterations to the vitreous humour of the eye in a rat model
KH Collins, W Herzog, RA Reimer, CR Reno, BJ Heard, DA Hart
Inflammation Research 67, 139-146, 2018
142018
Ligament and meniscus loading in the ovine stifle joint during normal gait
JM Rosvold, M Atarod, BJ Heard, EJ O'Brien, CB Frank, NG Shrive
The Knee 23 (1), 70-77, 2016
132016
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