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Kelsi Hall
Kelsi Hall
Verified email at nmbu.no
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Year
NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation
AV Sharrock, TS Mulligan, KR Hall, EM Williams, DT White, L Zhang, ...
Nature methods 19 (2), 205-215, 2022
342022
Primordial‐like enzymes from bacteria with reduced genomes
MP Ferla, JL Brewster, KR Hall, GB Evans, WM Patrick
Molecular Microbiology 105 (4), 508-524, 2017
342017
Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa
L Zhang, C Chen, J Fu, B Lilley, C Berlinicke, B Hansen, D Ding, G Wang, ...
Elife 10, e57245, 2021
152021
Reductants fuel lytic polysaccharide monooxygenase activity in a pH‐dependent manner
O Golten, I Ayuso‐Fernández, KR Hall, AA Stepnov, M Sørlie, ÅK Røhr, ...
FEBS letters 597 (10), 1363-1374, 2023
132023
Evaluation of NfsA-like nitroreductases from Neisseria meningitidis and Bartonella henselae for enzyme-prodrug therapy, targeted cellular ablation, and …
MH Rich, AV Sharrock, KR Hall, DF Ackerley, JK MacKichan
Biotechnology letters 40, 359-367, 2018
112018
Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues
KR Hall, KJ Robins, EM Williams, MH Rich, MJ Calcott, JN Copp, RF Little, ...
Elife 9, e59081, 2020
8*2020
Total Synthesis and Bioactivity Studies of Fungal Metabolite (−)-TAN-2483B
JAJ McCone, KK Somarathne, CL Orme, RJ Hewitt, ER Grant, KR Hall, ...
Organic Letters 22 (24), 9427-9432, 2020
72020
A conserved second sphere residue tunes copper site reactivity in lytic polysaccharide monooxygenases
KR Hall, C Joseph, I Ayuso-Fernández, A Tamhankar, L Rieder, R Skaali, ...
Journal of the American Chemical Society 145 (34), 18888-18903, 2023
62023
Mutational dissection of a hole hopping route that can be tuned to boost peroxygenase activity in LPMOs
VGH Eijsink, I Ayuso-Fernández, TZ Emrich-Mills, J Haak, O Golten, ...
2023
LPMO immobilization on Carbon nanotubes: a first investigation toward higher stability and catalytic activity
C Pontremoli, K Hall, M Bonomo, N Barbero, C Barolo, M Sørlie, V Eijsink, ...
-, 60-60, 2023
2023
Investigating the evolvability of'Escherichia coli nfsA'via simultaneous site-directed mutagenesis
K Hall
Open Access Te Herenga Waka-Victoria University of Wellington, 2019
2019
Using E. coli NfsA as a model to improve our understanding of enzyme engineering
KR Hall, K Robins, W Patrick, D Ackerley, A Sharrock, J Mumm
2019
Engineering bacterial nitroreductases for anticancer gene therapy and targeted cell ablation
A Sharrock, E Williams, V Arcus, J Mumm, D Ackerley
2017
Simultaneous randomisation of eight key active site residues in E. coli NfsA to generate superior nitroreductases for prodrug activation
KR Hall, K Robins, D Ackerley, M Rich, R Little, J Copp, A Sharrock, ...
2017
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