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Leona D. Samson
Leona D. Samson
Professor Emerita, Biological Engineering, Biology MIT
Email confirmado em mit.edu
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Citado por
Citado por
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The Lancet Commission on pollution and health
PJ Landrigan, R Fuller, NJR Acosta, O Adeyi, R Arnold, AB Baldé, ...
The lancet 391 (10119), 462-512, 2018
39222018
Balancing repair and tolerance of DNA damage caused by alkylating agents
D Fu, JA Calvo, LD Samson
Nature Reviews Cancer 12 (2), 104-120, 2012
10512012
A new pathway for DNA repair in Escherichia coli
L Samson, J Cairns
Nature 267 (5608), 281-283, 1977
9441977
Systematic discovery of in vivo phosphorylation networks
R Linding, LJ Jensen, GJ Ostheimer, MATM van Vugt, C Jørgensen, ...
Cell 129 (7), 1415-1426, 2007
8772007
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
LB Meira, JM Bugni, SL Green, CW Lee, B Pang, D Borenshtein, ...
The Journal of clinical investigation 118 (7), 2516-2525, 2008
6622008
Standardizing global gene expression analysis between laboratories and across platforms
Toxicogenomics Research Consortium Weis BK weis@ niehs. nih. gov 1 b
Nature methods 2 (5), 351-356, 2005
6022005
Global response of Saccharomyces cerevisiae to an alkylating agent
SA Jelinsky, LD Samson
Proceedings of the National Academy of Sciences 96 (4), 1486-1491, 1999
5311999
The human gut bacterial genotoxin colibactin alkylates DNA
MR Wilson, Y Jiang, PW Villalta, A Stornetta, PD Boudreau, A Carrá, ...
Science 363 (6428), eaar7785, 2019
4342019
ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
J Shen, Z Ju, W Zhao, L Wang, Y Peng, Z Ge, ZD Nagel, J Zou, C Wang, ...
Nature medicine 24 (5), 556-562, 2018
4222018
Base excision repair in yeast and mammals
A Memisoglu, L Samson
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 451 (1 …, 2000
4222000
Regulatory networks revealed by transcriptional profiling of damaged Saccharomyces cerevisiae cells: Rpn4 links base excision repair with proteasomes
SA Jelinsky, P Estep, GM Church, LD Samson
Molecular and cellular biology, 2000
4192000
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
MJ Hickman, LD Samson
Proceedings of the National Academy of Sciences 96 (19), 10764-10769, 1999
4001999
A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction
A Sivaraman, JK Leach, S Townsend, T Iida, BJ Hogan, DB Stolz, R Fry, ...
Current drug metabolism 6 (6), 569-591, 2005
3862005
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision
AY Lau, OD Schärer, L Samson, GL Verdine, T Ellenberger
Cell 95 (2), 249-258, 1998
3571998
A systems approach to mapping DNA damage response pathways
CT Workman, HC Mak, S McCuine, JB Tagne, M Agarwal, O Ozier, ...
Science 312 (5776), 1054-1059, 2006
3302006
Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase
BP Engelward, G Weeda, MD Wyatt, JLM Broekhof, J De Wit, I Donker, ...
Proceedings of the National Academy of Sciences 94 (24), 13087-13092, 1997
2991997
Activation of inflammation/NF-κB signaling in infants born to arsenic-exposed mothers
RC Fry, P Navasumrit, C Valiathan, JP Svensson, BJ Hogan, M Luo, ...
PLoS genetics 3 (11), e207, 2007
2902007
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG
AY Lau, MD Wyatt, BJ Glassner, LD Samson, T Ellenberger
Proceedings of the National Academy of Sciences 97 (25), 13573-13578, 2000
2862000
Inflammation-induced DNA damage, mutations and cancer
J Kay, E Thadhani, L Samson, B Engelward
DNA repair 83, 102673, 2019
2812019
Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines
L Samson, JL Schwartz
Nature 287 (5785), 861-863, 1980
2791980
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