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Joo M. Caio
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Differential interactions of rifabutin with human and bacterial membranes: implication for its therapeutic and toxic effects
M Pinheiro, M Arêde, C Nunes, JM Caio, C Moiteiro, M Lúcio, S Reis
Journal of medicinal chemistry 56 (2), 417-426, 2013
362013
Alkyl deoxy-arabino-hexopyranosides: Synthesis, surface properties, and biological activities
FVM Silva, M Goulart, J Justino, A Neves, F Santos, J Caio, S Lucas, ...
Bioorganic & medicinal chemistry 16 (7), 4083-4092, 2008
342008
The influence of rifabutin on human and bacterial membrane models: implications for its mechanism of action
M Pinheiro, C Nunes, JM Caio, C Moiteiro, M Lucio, G Brezesinski, S Reis
The Journal of Physical Chemistry B 117 (20), 6187-6193, 2013
332013
Evaluation of the binding ability of tetraaza [2] arene [2] triazine receptors anchoring l-alanine units for aromatic carboxylate anions
AI Vicente, JM Caio, J Sardinha, C Moiteiro, R Delgado, V Flix
Tetrahedron 68 (2), 670-680, 2012
322012
Effects of a novel antimycobacterial compound on the biophysical properties of a pulmonary surfactant model membrane
M Pinheiro, M Arde, JJ Giner-Casares, C Nunes, JM Caio, C Moiteiro, ...
International journal of pharmaceutics 450 (1-2), 268-277, 2013
272013
Interplay of mycolic acids, antimycobacterial compounds and pulmonary surfactant membrane: A biophysical approach to disease
M Pinheiro, JJ Giner-Casares, M Lcio, JM Caio, C Moiteiro, JLFC Lima, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (2), 896-905, 2013
262013
Drug–membrane interaction studies applied to N′-acetyl-rifabutin
M Pinheiro, M Arde, JM Caio, C Moiteiro, M Lcio, S Reis
European Journal of Pharmaceutics and Biopharmaceutics 85 (3), 597-603, 2013
202013
Azacalix [2] arene [2] triazine-based receptors bearing carboxymethyl pendant arms on nitrogen bridges: synthesis and evaluation of their coordination ability towards copper (II)
JM Caio, T Esteves, S Carvalho, C Moiteiro, V Flix
Organic & Biomolecular Chemistry 12 (4), 589-599, 2014
172014
Molecular interaction of rifabutin on model lung surfactant monolayers
M Pinheiro, M Lúcio, S Reis, JLFC Lima, JM Caio, C Moiteiro, ...
The Journal of Physical Chemistry B 116 (38), 11635-11645, 2012
152012
Evaluation of the structure–activity relationship of rifabutin and analogs: a drug–membrane study
M Pinheiro, C Pereira‐Leite, M Arde, C Nunes, JM Caio, C Moiteiro, ...
ChemPhysChem 14 (12), 2808-2816, 2013
122013
Tuning the bioactivity of tensioactive deoxy glycosides to structure: antibacterial activity versus selective cholinesterase inhibition rationalized by molecular docking
A Martins, MS Santos, C Dias, P Serra, V Cachatra, J Pais, J Caio, ...
European Journal of Organic Chemistry 2013 (8), 1448-1459, 2013
122013
Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis
IF Duarte, J Caio, MF Moedas, LA Rodrigues, AP Leandro, IA Rivera, ...
Cellular and Molecular Life Sciences, 1-18, 2021
52021
Interactions of N′-acetyl-rifabutin and N′-butanoyl-rifabutin with lipid bilayers: A synchrotron X-ray study
M Pinheiro, C Nunes, JM Caio, C Moiteiro, G Brezesinski, S Reis
International journal of pharmaceutics 453 (2), 560-568, 2013
42013
Drug-induced effects on urea cycle enzymes associate with altered ammonia metabolism, NAD+ biosynthesis and mitochondrial protein acetylome
MF Moedas, M Farelo, J Caio, A Pereira, L IJlst, RJA Wanders, MFB Silva
Free Radical Biology and Medicine 120, S108, 2018
2018
Alkyl deoxy-arabino-hexopyranosides: Synthesis, surface properties, and biological activities
M Oliveira, M Goulart, J Justino, A Neves, F Santos, J Caio, S Lucas, ...
Elsevier and Pergamon, 2008
2008
A NEW AND EASY APPROACH FOR THE SYNTHESIS OF METHYL 2-DEOXY-2-C-[(ETHOXYCARBONYL) METHYLENE] HEXOPYRANOSIDES
RG Lopes, JL Salta, JM Caio, AP Rauter
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Articles 1–16