| Evidence that TLR4 is not a receptor for saturated fatty acids but mediates lipid-induced inflammation by reprogramming macrophage metabolism GI Lancaster, KG Langley, NA Berglund, HL Kammoun, S Reibe, ... Cell metabolism 27 (5), 1096-1110. e5, 2018 | 391 | 2018 |
| TrackMate 7: integrating state-of-the-art segmentation algorithms into tracking pipelines D Ershov, MS Phan, JW Pylvänäinen, SU Rigaud, L Le Blanc, ... Nature methods 19 (7), 829-832, 2022 | 301 | 2022 |
| Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 238 | 2017 |
| Developments in preclinical cancer imaging: innovating the discovery of therapeutics JRW Conway, NO Carragher, P Timpson Nature reviews cancer 14 (5), 314-328, 2014 | 173 | 2014 |
| Three-dimensional cancer models mimic cell–matrix interactions in the tumour microenvironment D Herrmann, JRW Conway, C Vennin, A Magenau, WE Hughes, ... Carcinogenesis 35 (8), 1671-1679, 2014 | 147 | 2014 |
| Cholesterol regulates Syntaxin 6 trafficking at trans-Golgi network endosomal boundaries M Reverter, C Rentero, A Garcia-Melero, M Hoque, SV de Muga, ... Cell reports 7 (3), 883-897, 2014 | 117 | 2014 |
| The inositol polyphosphate 5-phosphatase PIPP regulates AKT1-dependent breast cancer growth and metastasis LM Ooms, LC Binge, EM Davies, P Rahman, JRW Conway, R Gurung, ... Cancer cell 28 (2), 155-169, 2015 | 111 | 2015 |
| A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ... Cell reports 21 (1), 274-288, 2017 | 94 | 2017 |
| SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer NLE Harris, C Vennin, JRW Conway, KL Vine, M Pinese, MJ Cowley, ... Oncogene 36 (30), 4288-4298, 2017 | 84 | 2017 |
| The tyrosine phosphatase PTPN14 (Pez) inhibits metastasis by altering protein trafficking L Belle, N Ali, A Lonic, X Li, JL Paltridge, S Roslan, D Herrmann, ... Science signaling 8 (364), ra18-ra18, 2015 | 82 | 2015 |
| Bringing TrackMate into the era of machine-learning and deep-learning D Ershov, MS Phan, JW Pylvänäinen, SU Rigaud, L Le Blanc, ... BioRxiv, 2021.09. 03.458852, 2021 | 80 | 2021 |
| Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine JRW Conway, D Herrmann, TRJ Evans, JP Morton, P Timpson Gut 68 (4), 742-758, 2019 | 77 | 2019 |
| ELF5 drives lung metastasis in luminal breast cancer through recruitment of Gr1+ CD11b+ myeloid-derived suppressor cells D Gallego-Ortega, A Ledger, DL Roden, AMK Law, A Magenau, ... PLoS biology 13 (12), e1002330, 2015 | 77 | 2015 |
| Cell matrix adhesion in cell migration JRW Conway, G Jacquemet Essays in biochemistry 63 (5), 535-551, 2019 | 76 | 2019 |
| Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease-and drug-dependent dynamic regulation of cell-cell junctions in live tissue Z Erami, D Herrmann, SC Warren, M Nobis, EJ McGhee, MC Lucas, ... Cell reports 14 (1), 152-167, 2016 | 68 | 2016 |
| Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer JRW Conway, SC Warren, D Herrmann, KJ Murphy, AS Cazet, C Vennin, ... Cell reports 23 (11), 3312-3326, 2018 | 65 | 2018 |
| Integrin adhesion complexes MR Chastney, JRW Conway, J Ivaska Current Biology 31 (10), R536-R542, 2021 | 62 | 2021 |
| Annexin A6—A multifunctional scaffold in cell motility T Grewal, M Hoque, JRW Conway, M Reverter, M Wahba, SS Beevi, ... Cell adhesion & migration 11 (3), 288-304, 2017 | 58 | 2017 |
| Annexin A6 and late endosomal cholesterol modulate integrin recycling and cell migration A García-Melero, M Reverter, M Hoque, E Meneses-Salas, M Koese, ... Journal of Biological Chemistry 291 (3), 1320-1335, 2016 | 58 | 2016 |
| MASTL overexpression promotes chromosome instability and metastasis in breast cancer S Rogers, RA McCloy, BL Parker, D Gallego-Ortega, AMK Law, VT Chin, ... Oncogene 37 (33), 4518-4533, 2018 | 56 | 2018 |
