Genetic risk factors in Parkinson’s disease KJ Billingsley, S Bandres-Ciga, S Saez-Atienzar, AB Singleton Cell and tissue research 373, 9-20, 2018 | 227 | 2018 |
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture R Chia, MS Sabir, S Bandres-Ciga, S Saez-Atienzar, RH Reynolds, ... Nature genetics 53 (3), 294-303, 2021 | 218 | 2021 |
Cellular senescence and Alzheimer disease: the egg and the chicken scenario S Saez-Atienzar, E Masliah Nature Reviews Neuroscience 21 (8), 433-444, 2020 | 189 | 2020 |
LRRK2 mediates tubulation and vesicle sorting from lysosomes L Bonet-Ponce, A Beilina, CD Williamson, E Lindberg, JH Kluss, ... Science advances 6 (46), eabb2454, 2020 | 154 | 2020 |
The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling S Saez-Atienzar, L Bonet-Ponce, JR Blesa, FJ Romero, MP Murphy, ... Cell death & disease 5 (8), e1368-e1368, 2014 | 111 | 2014 |
Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease S Bandres-Ciga, S Saez-Atienzar, JJ Kim, MB Makarious, F Faghri, ... Acta neuropathologica 140, 341-358, 2020 | 80 | 2020 |
The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease S Bandres‐Ciga, S Saez‐Atienzar, L Bonet‐Ponce, K Billingsley, D Vitale, ... Movement Disorders 34 (4), 460-468, 2019 | 79 | 2019 |
On the mechanism underlying ethanol-induced mitochondrial dynamic disruption and autophagy response L Bonet-Ponce, S Saez-Atienzar, C da Casa, M Flores-Bellver, JM Barcia, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (7 …, 2015 | 69 | 2015 |
Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types S Saez-Atienzar, S Bandres-Ciga, RG Langston, JJ Kim, SW Choi, ... Science advances 7 (3), eabd9036, 2021 | 67 | 2021 |
The Parkinson’s disease protein LRRK2 interacts with the GARP complex to promote retrograde transport to the trans-Golgi network A Beilina, L Bonet-Ponce, R Kumaran, JJ Kordich, M Ishida, A Mamais, ... Cell reports 31 (5), 2020 | 62 | 2020 |
Characterization of mitophagy in the 6-hydoxydopamine Parkinson’s disease model ME Solesio, S Saez-Atienzar, J Jordán, MF Galindo Toxicological Sciences 129 (2), 411-420, 2012 | 59 | 2012 |
3‐Nitropropionic acid induces autophagy by forming mitochondrial permeability transition pores rather than activatiing the mitochondrial fission pathway ME Solesio, S Saez‐Atienzar, J Jordan, MF Galindo British journal of pharmacology 168 (1), 63-75, 2013 | 56 | 2013 |
The genetic architecture of Parkinson disease in Spain: characterizing population‐specific risk, differential haplotype structures, and providing etiologic insight S Bandres‐Ciga, S Ahmed, MS Sabir, C Blauwendraat, ... Movement Disorders 34 (12), 1851-1863, 2019 | 54 | 2019 |
Identification of genetic risk loci and prioritization of genes and pathways for myasthenia gravis: a genome-wide association study R Chia, S Saez-Atienzar, N Murphy, A Chiò, C Blauwendraat, ... Proceedings of the National Academy of Sciences 119 (5), e2108672119, 2022 | 53 | 2022 |
Distinct connectivity and functionality of aldehyde dehydrogenase 1a1-positive nigrostriatal dopaminergic neurons in motor learning J Wu, J Kung, J Dong, L Chang, C Xie, A Habib, S Hawes, N Yang, ... Cell reports 28 (5), 1167-1181. e7, 2019 | 52 | 2019 |
Autophagy and mitochondrial alterations in human retinal pigment epithelial cells induced by ethanol: implications of 4-hydroxy-nonenal M Flores-Bellver, L Bonet-Ponce, JM Barcia, JM Garcia-Verdugo, ... Cell death & disease 5 (7), e1328-e1328, 2014 | 50 | 2014 |
Rotenone induces the formation of 4-hydroxynonenal aggresomes. Role of ROS-mediated tubulin hyperacetylation and autophagic flux disruption L Bonet-Ponce, S Saez-Atienzar, C Da Casa, J Sancho-Pelluz, JM Barcia, ... Molecular neurobiology 53, 6194-6208, 2016 | 49 | 2016 |
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function DM Baron, AR Fenton, S Saez-Atienzar, A Giampetruzzi, A Sreeram, ... Cell reports 39 (1), 2022 | 48 | 2022 |
Glutathione-sensitive nanoplatform for monitored intracellular delivery and controlled release of Camptothecin C Muniesa, V Vicente, M Quesada, S Sáez-Atiénzar, JR Blesa, I Abasolo, ... RSC advances 3 (35), 15121-15131, 2013 | 24 | 2013 |
ALDH1A1 regulates postsynaptic μ–opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling J Pan, J Yu, L Sun, C Xie, L Chang, J Wu, S Hawes, S Saez–Atienzar, ... Scientific Reports 9 (1), 3602, 2019 | 23 | 2019 |