| Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels S Schlegel, E Rujas, AJ Ytterberg, RA Zubarev, J Luirink, JW De Gier Microbial cell factories 12, 1-12, 2013 | 162 | 2013 |
| The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region*♦ B Apellániz, E Rujas, S Serrano, K Morante, K Tsumoto, JMM Caaveiro, ... Journal of Biological Chemistry 290 (21), 12999-13015, 2015 | 55 | 2015 |
| Cholesterol-dependent membrane fusion induced by the gp41 membrane-proximal external region–transmembrane domain connection suggests a mechanism for broad HIV-1 neutralization B Apellániz, E Rujas, P Carravilla, J Requejo-Isidro, N Huarte, C Domene, ... Journal of virology 88 (22), 13367-13377, 2014 | 47 | 2014 |
| Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers E Rujas, I Kucharska, YZ Tan, S Benlekbir, H Cui, T Zhao, GA Wasney, ... Nature Communications 12 (1), 3661, 2021 | 46 | 2021 |
| Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface E Rujas, JMM Caaveiro, A Partida-Hanon, N Gulzar, K Morante, ... Scientific reports 6 (1), 38177, 2016 | 45 | 2016 |
| Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions P Carravilla, J Chojnacki, E Rujas, S Insausti, E Largo, D Waithe, ... Nature communications 10 (1), 78, 2019 | 38 | 2019 |
| Tailoring Escherichia coli for the l-Rhamnose PBAD Promoter-Based Production of Membrane and Secretory Proteins A Hjelm, A Karyolaimos, Z Zhang, E Rujas, D Vikstrom, DJ Slotboom, ... ACS synthetic biology 6 (6), 985-994, 2017 | 34 | 2017 |
| Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: implications for antibody recognition mechanism and immunogen design S Serrano, A Araujo, B Apellániz, S Bryson, P Carravilla, I de la Arada, ... Journal of Biological Chemistry 289 (10), 6565-6580, 2014 | 33 | 2014 |
| Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies E Rujas, H Cui, T Sicard, A Semesi, JP Julien Nature Communications 11 (1), 5066, 2020 | 29 | 2020 |
| Functional optimization of broadly neutralizing HIV-1 antibody 10E8 by promotion of membrane interactions E Rujas, DP Leaman, S Insausti, L Ortigosa-Pascual, L Zhang, MB Zwick, ... Journal of virology 92 (8), 10.1128/jvi. 02249-17, 2018 | 29 | 2018 |
| Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice MT Mabrouk, K Chiem, E Rujas, WC Huang, D Jahagirdar, B Quinn, ... Science advances 7 (49), eabj1476, 2021 | 27 | 2021 |
| Structural and thermodynamic basis of epitope binding by neutralizing and nonneutralizing forms of the anti-HIV-1 antibody 4E10 E Rujas, N Gulzar, K Morante, K Tsumoto, JK Scott, JL Nieva, ... Journal of virology 89 (23), 11975-11989, 2015 | 25 | 2015 |
| Dual inhibition of vacuolar-ATPase and TMPRSS2 is required for complete blockade of SARS-CoV-2 entry into cells S Icho, E Rujas, K Muthuraman, J Tam, H Liang, S Landreth, M Liao, ... Antimicrobial Agents and Chemotherapy 66 (7), e00439-22, 2022 | 20 | 2022 |
| Engineering pan–HIV-1 neutralization potency through multispecific antibody avidity E Rujas, H Cui, J Burnie, CB Aschner, T Zhao, S Insausti, K Muthuraman, ... Proceedings of the National Academy of Sciences 119 (4), e2112887119, 2022 | 14 | 2022 |
| Functional contacts between MPER and the anti-HIV-1 broadly neutralizing antibody 4E10 extend into the core of the membrane E Rujas, S Insausti, M García-Porras, R Sánchez-Eugenia, K Tsumoto, ... Journal of molecular biology 429 (8), 1213-1226, 2017 | 14 | 2017 |
| Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease MG Sugiyama, H Cui, DS Redka, M Karimzadeh, E Rujas, H Maan, ... Scientific reports 11 (1), 23315, 2021 | 12 | 2021 |
| Affinity for the interface underpins potency of antibodies operating in membrane environments E Rujas, S Insausti, DP Leaman, P Carravilla, S González-Resines, ... Cell reports 32 (7), 2020 | 10 | 2020 |
| Exposure of the HIV-1 broadly neutralizing antibody 10E8 MPER epitope on the membrane surface by gp41 transmembrane domain scaffolds V Oakes, J Torralba, E Rujas, JL Nieva, C Domene, B Apellaniz Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (6), 1259-1271, 2018 | 10 | 2018 |
| Peripheral membrane interactions boost the engagement by an anti-HIV-1 broadly neutralizing antibody E Rujas, JMM Caaveiro, S Insausti, M García-Porras, K Tsumoto, JL Nieva Journal of Biological Chemistry 292 (13), 5571-5583, 2017 | 10 | 2017 |
| Cholesterol constrains the antigenic configuration of the membrane-proximal neutralizing HIV-1 epitope J Torralba, I de la Arada, P Carravilla, S Insausti, E Rujas, E Largo, ... ACS Infectious Diseases 6 (8), 2155-2168, 2020 | 9 | 2020 |
Jean-Philippe JulienScientist, Hospital for Sick Children Research InstituteEmail confirmado em sickkids.ca
