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Lara Perryman
Lara Perryman
Email confirmado em bric.ku.dk
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RETRACTED ARTICLE: The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase
TR Cox, RMH Rumney, EM Schoof, L Perryman, AM Høye, A Agrawal, ...
Nature 522 (7554), 106-110, 2015
5582015
Paediatric and adult malignant glioma: close relatives or distant cousins?
C Jones, L Perryman, D Hargrave
Nature reviews Clinical oncology 9 (7), 400-413, 2012
2112012
MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase–mediated HOX/stem cell gene signature
N Gaspar, L Marshall, L Perryman, DA Bax, SE Little, M Viana-Pereira, ...
Cancer research 70 (22), 9243-9252, 2010
2022010
Kinome-wide decoding of network-attacking mutations rewiring cancer signaling
P Creixell, EM Schoof, CD Simpson, J Longden, CJ Miller, HJ Lou, ...
Cell 163 (1), 202-217, 2015
1832015
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development
DA Bax, SE Little, N Gaspar, L Perryman, L Marshall, M Viana-Pereira, ...
PloS one 4 (4), e5209, 2009
1332009
EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines
DA Bax, N Gaspar, SE Little, L Marshall, L Perryman, M Regairaz, ...
Clinical cancer research 15 (18), 5753-5761, 2009
992009
The lysyl oxidase like 2/3 enzymatic inhibitor, PXS‐5153A, reduces crosslinks and ameliorates fibrosis
H Schilter, AD Findlay, L Perryman, TT Yow, J Moses, A Zahoor, CI Turner, ...
Journal of cellular and molecular medicine 23 (3), 1759-1770, 2019
912019
Enhanced efficacy of IGF1R inhibition in pediatric glioblastoma by combinatorial targeting of PDGFRα/β
A Bielen, L Perryman, GM Box, M Valenti, A de Haven Brandon, V Martins, ...
Molecular cancer therapeutics 10 (8), 1407-1418, 2011
712011
Lysyl oxidase in cancer research
L Perryman, JT Erler
Future oncology 10 (9), 1709-1717, 2014
692014
Etoposide improves survival in high-grade glioma: a meta-analysis
A Leonard, JE Wolff
Anticancer research 33 (8), 3307-3315, 2013
422013
Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition
A Bielen, G Box, L Perryman, L Bjerke, S Popov, Y Jamin, A Jury, ...
Proceedings of the National Academy of Sciences 109 (20), E1267-E1276, 2012
312012
Evaluation of the response of intracranial xenografts to VEGF signaling inhibition using multiparametric MRI
JKR Boult, G Box, M Vinci, L Perryman, SA Eccles, C Jones, SP Robinson
Neoplasia 19 (9), 684-694, 2017
162017
Investigating intracranial tumour growth patterns with multiparametric MRI incorporating Gd‐DTPA and USPIO‐enhanced imaging
JKR Boult, M Borri, A Jury, S Popov, G Box, L Perryman, SA Eccles, ...
NMR in Biomedicine 29 (11), 1608-1617, 2016
152016
An activity‐based bioprobe differentiates a novel small molecule inhibitor from a LOXL2 antibody and provides renewed promise for anti‐fibrotic therapeutic strategies
A Findlay, C Turner, H Schilter, M Deodhar, W Zhou, L Perryman, J Foot, ...
Clinical and Translational Medicine 11 (11), 2021
142021
Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo
LA Perryman, JM Blair, EA Kingsley, B Szymanska, KT Ow, VW Wen, ...
Biochemical and biophysical research communications 345 (3), 1207-1214, 2006
142006
Comparison of 18F-FET and 18F-FLT small animal PET for the assessment of anti-VEGF treatment response in an orthotopic model of glioblastoma
MK Nedergaard, SR Michaelsen, L Perryman, J Erler, HS Poulsen, ...
Nuclear Medicine and Biology 43 (3), 198-205, 2016
132016
Brain cancer spreads
L Perryman, JT Erler
Science Translational Medicine 6 (247), 247fs28-247fs28, 2014
102014
Fibrosis in Mesothelioma: Potential Role of Lysyl Oxidases
L Perryman, SG Gray
Cancers 14 (4), 981, 2022
52022
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer
JL Chitty, M Yam, L Perryman, AL Parker, JN Skhinas, YFI Setargew, ...
Nature Cancer 4 (9), 1326-1344, 2023
42023
PROTACs targeting MLKL protect cells from necroptosis
OH Rathje, L Perryman, RJ Payne, DW Hamprecht
Journal of Medicinal Chemistry 66 (16), 11216-11236, 2023
32023
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