Pedro Cravo
Pedro Cravo
Global Health and Tropical Medicine/IHMT/Universidade Nova de Lisboa
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Malaria parasites can develop stable resistance to artemisinin but lack mutations in candidate genes atp6 (encoding the sarcoplasmic and endoplasmic reticulum Ca2+ ATPase …
A Afonso, P Hunt, S Cheesman, AC Alves, CV Cunha, V Do Rosário, ...
Antimicrobial agents and chemotherapy 50 (2), 480-489, 2006
Gene encoding a deubiquitinating enzyme is mutated in artesunate‐ and chloroquine‐resistant rodent malaria parasites§
P Hunt, A Afonso, A Creasey, R Culleton, ABS Sidhu, J Logan, ...
Molecular microbiology 65 (1), 27-40, 2007
Real-time quantitative PCR with SYBR Green I detection for estimating copy numbers of nine drug resistance candidate genes in Plasmodium falciparum
ID Ferreira, VE Do Rosário, PVL Cravo
Malaria journal 5 (1), 1, 2006
Chalcone derivatives: promising starting points for drug design
MN Gomes, EN Muratov, M Pereira, JC Peixoto, LP Rosseto, PVL Cravo, ...
Molecules 22 (8), 1210, 2017
Of mice and malaria mutants: unravelling the genetics of drug resistance using rodent malaria models
JMR Carlton, K Hayton, PVL Cravo, D Walliker
Trends in parasitology 17 (5), 236-242, 2001
Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand
D Lopes, K Rungsihirunrat, F Nogueira, A Seugorn, JP Gil, VE Do Rosário, ...
Malaria journal 1 (1), 12, 2002
Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation
P Brasil, MG Zalis, A de Pina-Costa, AM Siqueira, CB Júnior, S Silva, ...
The Lancet Global Health 5 (10), e1038-e1046, 2017
Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing
RL Culleton, T Mita, M Ndounga, H Unger, PVL Cravo, GM Paganotti, ...
Malaria journal 7 (1), 174, 2008
Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites
P Hunt, A Martinelli, K Modrzynska, S Borges, A Creasey, L Rodrigues, ...
BMC genomics 11 (1), 499, 2010
Chloroquine resistance in Plasmodium chabaudi: are chloroquine-resistance transporter (crt) and multi-drug resistance (mdr1) orthologues involved?
P Hunt, PVL Cravo, P Donleavy, JMR Carlton, D Walliker
Molecular and biochemical parasitology 133 (1), 27-35, 2004
Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites
B Franke-Fayard, D Djokovic, MW Dooren, J Ramesar, AP Waters, ...
International journal for parasitology 38 (14), 1651-1662, 2008
Detection of atovaquone and Malarone™ resistance conferring mutations in Plasmodium falciparum cytochrome b gene (cytb)
JP Gil, F Nogueira, J Strömberg-Nörklit, J Lindberg, M Carrolo, ...
Molecular and cellular probes 17 (2-3), 85-89, 2003
Genetics of mefloquine resistance in the rodent malaria parasite Plasmodium chabaudi
PVL Cravo, JMR Carlton, P Hunt, L Bisoni, RA Padua, D Walliker
Antimicrobial agents and chemotherapy 47 (2), 709-718, 2003
Dipeptide derivatives of primaquine as transmission-blocking antimalarials: effect of aliphatic side-chain acylation on the gametocytocidal activity and on the formation of …
MJ Portela, R Moreira, E Valente, L Constantino, J Iley, J Pinto, R Rosa, ...
Pharmaceutical research 16 (6), 949-955, 1999
Plasmodium falciparum from Pará state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA‐type PfATPase6
ID Ferreira, A Martinelli, LA Rodrigues, EL Do Carmo, VE Do Rosário, ...
Tropical Medicine & International Health 13 (2), 199-207, 2008
Emerging Plasmodium vivax resistance to chloroquine in South America: an overview
LA Gonçalves, P Cravo, MU Ferreira
Memorias do Instituto Oswaldo Cruz 109 (5), 534-539, 2014
Geographic structuring of the Plasmodium falciparum sarco (endo) plasmic reticulum Ca2+ ATPase (PfSERCA) gene diversity
R Jambou, A Martinelli, J Pinto, S Gribaldo, E Legrand, M Niang, N Kim, ...
PLoS One 5 (2), 2010
Natural products as leads in schistosome drug discovery
BJ Neves, CH Andrade, PVL Cravo
Molecules 20 (2), 1872-1903, 2015
In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance‐associated mutations of Plasmodium falciparum from …
ID Ferreira, D Lopes, A Martinelli, C Ferreira, VE Do Rosário, P Cravo
Tropical Medicine & International Health 12 (3), 353-362, 2007
Plasmodium falciparum: gene mutations and amplification of dihydrofolate reductase genes in parasites grown in vitro in presence of pyrimethamine
S Thaithong, LC Ranford-Cartwright, N Siripoon, P Harnyuttanakorn, ...
Experimental parasitology 98 (2), 59-70, 2001
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