| Protein recognition by short peptide reversible inhibitors of the chromatin-modifying LSD1/CoREST lysine demethylase M Tortorici, MT Borrello, M Tardugno, LR Chiarelli, S Pilotto, G Ciossani, ... ACS chemical biology 8 (8), 1677-1682, 2013 | 81 | 2013 |
| cis‐cyclopropylamines as mechanism‐based inhibitors of monoamine oxidases T Malcomson, K Yelekci, MT Borrello, A Ganesan, E Semina, N De Kimpe, ... The FEBS Journal 282 (16), 3190-3198, 2015 | 37 | 2015 |
| Expanding the druggable space of the LSD1/CoREST epigenetic target: new potential binding regions for drug-like molecules, peptides, protein partners, and chromatin JC Robertson, NC Hurley, M Tortorici, G Ciossani, MT Borrello, ... PLoS computational biology 9 (7), e1003158, 2013 | 37 | 2013 |
| Efficient synthesis and biological evaluation of proximicins A, B and C F Brucoli, A Natoli, P Marimuthu, MT Borrello, P Stapleton, S Gibbons, ... Bioorganic & medicinal chemistry 20 (6), 2019-2024, 2012 | 37 | 2012 |
| Evidencing a pancreatic ductal adenocarcinoma subpopulation sensitive to the proteasome inhibitor carfilzomib NA Fraunhoffer, AM Abuelafia, M Bigonnet, O Gayet, J Roques, E Telle, ... Clinical Cancer Research 26 (20), 5506-5519, 2020 | 25 | 2020 |
| LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models S Regufe da Mota, S Bailey, RA Strivens, AL Hayden, LR Douglas, ... Cancer Cell International 18, 1-9, 2018 | 25 | 2018 |
| Fluorinated tranylcypromine analogues as inhibitors of lysine-specific demethylase 1 (LSD1, KDM1A) MT Borrello, B Schinor, K Bartels, H Benelkebir, S Pereira, WT Al-Jamal, ... Bioorganic & Medicinal Chemistry Letters 27 (10), 2099-2101, 2017 | 24 | 2017 |
| Structural characterization and antimicrobial evaluation of atractyloside, atractyligenin, and 15-didehydroatractyligenin methyl ester F Brucoli, MT Borrello, P Stapleton, GN Parkinson, S Gibbons Journal of Natural Products 75 (6), 1070-1075, 2012 | 19 | 2012 |
| Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer N Azizi, J Toma, M Martin, MF Khalid, F Mousavi, PW Win, MT Borrello, ... Oncogene 40 (17), 3118-3135, 2021 | 18 | 2021 |
| The unfolded protein response: An emerging therapeutic target for pancreatitis and pancreatic ductal adenocarcinoma MT Borrello, MB Martin, CL Pin Pancreatology 22 (1), 148-159, 2022 | 10 | 2022 |
| NUPR1 interacts with eIF2α and is required for resolution of the ER stress response in pancreatic tissue MT Borrello, P Santofimia‐Castaño, M Bocchio, A Listi, N Fraunhoffer, ... The FEBS Journal 288 (13), 4081-4097, 2021 | 9 | 2021 |
| Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in … V Coutinho Carneiro, IC de Abreu da Silva, MS Amaral, ASA Pereira, ... PLoS Neglected Tropical Diseases 14 (7), e0008332, 2020 | 9* | 2020 |
| Isoform-selective HDAC1/6/8 inhibitors with an imidazo-ketopiperazine cap containing stereochemical diversity B Lecointre, R Narozny, MT Borrello, J Senger, A Chakrabarti, M Jung, ... Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 9 | 2018 |
| Chronic liver diseases: From development to novel pharmacological therapies: IUPHAR Review 37 MT Borrello, D Mann British Journal of Pharmacology 180 (22), 2880-2897, 2023 | 8 | 2023 |
| NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response MT Borrello, MR Emma, A Listi, M Rubis, S Coslet, G Augello, ... bioRxiv, 2020.10. 23.350652, 2020 | 8 | 2020 |
| Synthesis of Carboxamide‐Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia M Teresa Borrello, H Benelkebir, A Lee, C Hin Tam, M Shafat, ... ChemMedChem 16 (8), 1316-1324, 2021 | 4 | 2021 |
| LSD (Lysine-Specific Demethylase): A Decade-Long Trip from Discovery to Clinical Trials A Lee, MT Borrello, A Ganesan Epigenetic Drug Discovery, 221-261, 2019 | 2 | 2019 |
| Traditional Knowledge Evolution over Half of a Century: Local Herbal Resources and Their Changes in the Upper Susa Valley of Northwest Italy N Sulaiman, DM Zocchi, MT Borrello, G Mattalia, L Antoniazzi, ... Plants 13 (1), 43, 2023 | 1 | 2023 |
| Synthesis of carboxamides tranylcypromine analogues as LSD1 (KDM1A) inhibitors for AML T Borrello, CH Tam, M Shafat, S Rushworth, K Bowles, S Bailey, S Crabb, ... | 1 | 2021 |
| Discovery of novel small molecule inhibitors of HDAC6 that suppress liver fibrosis MT Borrello, D Ružić, F Oakley, K Nikolić, J Mann, D Mann Journal of Hepatology 78 (S1), 2023 | | 2023 |
A GanesanProfessor of Chemical Biology, University of East AngliaVerified email at uea.ac.uk
