| Lest we forget you—methylene blue… RH Schirmer, H Adler, M Pickhardt, E Mandelkow Neurobiology of aging 32 (12), 2325. e7-2325. e16, 2011 | 476 | 2011 |
| Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs I Khlistunova, J Biernat, Y Wang, M Pickhardt, M von Bergen, Z Gazova, ... Journal of Biological Chemistry 281 (2), 1205-1214, 2006 | 455 | 2006 |
| Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells M Pickhardt, Z Gazova, M von Bergen, I Khlistunova, Y Wang, A Hascher, ... Journal of Biological Chemistry 280 (5), 3628-3635, 2005 | 442 | 2005 |
| Development of tau aggregation inhibitors for Alzheimer's disease B Bulic, M Pickhardt, B Schmidt, EM Mandelkow, H Waldmann, ... Angewandte Chemie International Edition 48 (10), 1740-1752, 2009 | 310 | 2009 |
| Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model YP Wang, J Biernat, M Pickhardt, E Mandelkow, EM Mandelkow Proceedings of the National Academy of Sciences 104 (24), 10252-10257, 2007 | 221 | 2007 |
| Tau protein and tau aggregation inhibitors B Bulic, M Pickhardt, EM Mandelkow, E Mandelkow Neuropharmacology 59 (4-5), 276-289, 2010 | 217 | 2010 |
| Curcumin‐derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease? R Narlawar, M Pickhardt, S Leuchtenberger, K Baumann, S Krause, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (1), 165-172, 2008 | 205 | 2008 |
| Rhodanine-based tau aggregation inhibitors in cell models of tauopathy B Bulic, M Pickhardt, I Khlistunova, J Biernat, EM Mandelkow, ... ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH- 46 (48), 9215, 2007 | 184 | 2007 |
| The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis M von Bergen, S Barghorn, SA Müller, M Pickhardt, J Biernat, ... Biochemistry 45 (20), 6446-6457, 2006 | 164 | 2006 |
| Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of τ aggregation and toxicity in vitro and in cells M Pickhardt, G Larbig, I Khlistunova, A Coksezen, B Meyer, ... Biochemistry 46 (35), 10016-10023, 2007 | 154 | 2007 |
| Mechanistic basis of phenothiazine‐driven inhibition of Tau aggregation E Akoury, M Pickhardt, M Gajda, J Biernat, E Mandelkow, M Zweckstetter Angewandte Chemie International Edition 52 (12), 3511-3515, 2013 | 150 | 2013 |
| Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau K Hochgräfe, A Sydow, D Matenia, D Cadinu, S Könen, O Petrova, ... Acta neuropathologica communications 3, 1-22, 2015 | 148 | 2015 |
| Cellular and humoral immune response in progressive multifocal leukoencephalopathy F Weber, C Goldmann, M Krämer, FJ Kaup, M Pickhardt, P Young, H Petry, ... Annals of neurology 49 (5), 636-642, 2001 | 138 | 2001 |
| Progress and developments in tau aggregation inhibitors for Alzheimer disease B Bulic, M Pickhardt, E Mandelkow Journal of medicinal chemistry 56 (11), 4135-4155, 2013 | 126 | 2013 |
| Screening for inhibitors of tau polymerization M Pickhardt, M Bergen, Z Gazova, A Hascher, J Biernat, EM Mandelkow, ... Current alzheimer research 2 (2), 219-226, 2005 | 98 | 2005 |
| Inhibition of tau filament formation by conformational modulation E Akoury, M Gajda, M Pickhardt, J Biernat, P Soraya, C Griesinger, ... Journal of the American Chemical Society 135 (7), 2853-2862, 2013 | 90 | 2013 |
| Screening for inhibitors of tau protein aggregation into Alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping G Larbig, M Pickhardt, DG Lloyd, B Schmidt, E Mandelkow Current Alzheimer Research 4 (3), 315-323, 2007 | 73 | 2007 |
| Inhibition of tau aggregation in cell models of tauopathy I Khlistunova, M Pickhardt, J Biernat, Y Wang, EM Mandelkow, ... Current Alzheimer Research 4 (5), 544-546, 2007 | 70 | 2007 |
| N-phenylamine derivatives as aggregation inhibitors in cell models of tauopathy M Pickhardt, J Biernat, I Khlistunova, YP Wang, Z Gazova, EM Mandelkow, ... Current Alzheimer Research 4 (4), 397-402, 2007 | 66 | 2007 |
| Identification of small molecule inhibitors of tau aggregation by targeting monomeric tau as a potential therapeutic approach for tauopathies M Pickhardt, T Neumann, D Schwizer, K Callaway, M Vendruscolo, ... Current Alzheimer Research 12 (9), 814-828, 2015 | 61 | 2015 |
