Jeroen van de Peppel
Jeroen van de Peppel
Erasmus MC
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A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
AMC Barradas, HAM Fernandes, N Groen, YC Chai, J Schrooten, ...
Biomaterials 33 (11), 3205-3215, 2012
Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets
J van de Peppel, N Kettelarij, H van Bakel, TTJP Kockelkorn, ...
Molecular cell 19 (4), 511-522, 2005
Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects
C Medina-Gomez, JP Kemp, K Trajanoska, J Luan, A Chesi, TS Ahluwalia, ...
The American Journal of Human Genetics 102 (1), 88-102, 2018
Monitoring global messenger RNA changes in externally controlled microarray experiments
J van de Peppel, P Kemmeren, H van Bakel, M Radonjic, D van Leenen, ...
EMBO reports 4 (4), 387-393, 2003
MicroRNA functions in osteogenesis and dysfunctions in osteoporosis
AJ Van Wijnen, J Van De Peppel, JP Van Leeuwen, JB Lian, GS Stein, ...
Current osteoporosis reports 11, 72-82, 2013
Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA
JC Andrau, L van de Pasch, P Lijnzaad, T Bijma, MG Koerkamp, ...
Molecular cell 22 (2), 179-192, 2006
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course
M Graff, JS Ngwa, T Workalemahu, G Homuth, S Schipf, A Teumer, ...
Human molecular genetics 22 (17), 3597-3607, 2013
Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment
JP Kemp, C Medina-Gomez, K Estrada, B St Pourcain, DHM Heppe, ...
PLoS genetics 10 (6), e1004423, 2014
Vitamin D and gene networks in human osteoblasts
J van de Peppel, JPTM van Leeuwen
Frontiers in Physiology 5, 137, 2014
Calcifying vascular smooth muscle cells and osteoblasts: independent cell types exhibiting extracellular matrix and biomineralization-related mimicries
RDAM Alves, M Eijken, J van de Peppel, JPTM van Leeuwen
BMC genomics 15 (1), 1-14, 2014
A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone
C Bruedigam, M Eijken, M Koedam, J Van De Peppel, K Drabek, H Chiba, ...
Stem cells 28 (5), 916-927, 2010
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway
AM Brum, J van de Peppel, CS Van Der Leije, M Schreuders-Koedam, ...
Proceedings of the National Academy of Sciences 112 (41), 12711-12716, 2015
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
C Medina-Gomez, JP Kemp, NL Dimou, E Kreiner, A Chesi, BS Zemel, ...
Nature communications 8 (1), 121, 2017
Identification of three early phases of cell-fate determination during osteogenic and adipogenic differentiation by transcription factor dynamics
J van de Peppel, T Strini, J Tilburg, H Westerhoff, AJ van Wijnen, ...
Stem cell reports 8 (4), 947-960, 2017
Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth
J Morhayim, J van de Peppel, JAA Demmers, G Kocer, AL Nigg, ...
The FASEB Journal 29 (1), 274-285, 2015
Basic techniques in human mesenchymal stem cell cultures: differentiation into osteogenic and adipogenic lineages, genetic perturbations, and phenotypic analyses
C Bruedigam, M Driel, M Koedam, J Peppel, BCJ van der Eerden, ...
Current protocols in stem cell biology 17 (1), 1H. 3.1-1H. 3.20, 2011
GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release
K Drabek, J van de Peppel, M Eijken, JPTM van Leeuwen
Journal of Bone and Mineral Research 26 (9), 2045-2051, 2011
Human memory Th17 cell populations change into anti-inflammatory cells with regulatory capacity upon exposure to active vitamin D
W Dankers, N Davelaar, JP Van Hamburg, J Van De Peppel, EM Colin, ...
Frontiers in immunology 10, 1504, 2019
Pro-osteogenic trophic effects by PKA activation in human mesenchymal stromal cells
J Doorn, J van de Peppel, JPTM van Leeuwen, N Groen, ...
Biomaterials 32 (26), 6089-6098, 2011
Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns
NRM Beijer, ZM Nauryzgaliyeva, EM Arteaga, L Pieuchot, K Anselme, ...
Scientific reports 9 (1), 9099, 2019
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