Carlo Sala Frigerio
Carlo Sala Frigerio
UK Dementia Research Institute
Email confirmado em ucl.ac.uk
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Alteration of the micro RNA network during the progression of Alzheimer's disease
P Lau, K Bossers, R Janky, E Salta, CS Frigerio, S Barbash, R Rothman, ...
EMBO molecular medicine 5 (10), 1613-1634, 2013
3452013
The APP family of proteins: similarities and differences
DM Walsh, AM Minogue, C Sala Frigerio, JV Fadeeva, W Wasco, ...
Biochemical Society Transactions 35 (2), 416-420, 2007
1542007
The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ plaques
CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ...
Cell reports 27 (4), 1293-1306. e6, 2019
1232019
Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease
CS Frigerio, P Lau, E Salta, J Tournoy, K Bossers, R Vandenberghe, ...
Neurology 81 (24), 2103-2106, 2013
1052013
Alzheimer's disease mechanisms and emerging roads to novel therapeutics
C Sala Frigerio, B De Strooper
Annual review of neuroscience 39, 57-79, 2016
832016
Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation
GG Borlikova, M Trejo, AJ Mably, JM Mc Donald, CS Frigerio, CM Regan, ...
Neurobiology of aging 34 (5), 1315-1327, 2013
732013
On the identification of low allele frequency mosaic mutations in the brains of Alzheimer's disease patients
CS Frigerio, P Lau, C Troakes, V Deramecourt, P Gele, P Van Loo, T Voet, ...
Alzheimer's & Dementia 11 (11), 1265-1276, 2015
582015
Spatial transcriptomics and in situ sequencing to study Alzheimer’s disease
WT Chen, A Lu, K Craessaerts, B Pavie, CS Frigerio, N Corthout, X Qian, ...
Cell 182 (4), 976-991. e19, 2020
512020
N-terminal extensions retard Aβ42 fibril formation but allow cross-seeding and coaggregation with Aβ42
O Szczepankiewicz, B Linse, G Meisl, E Thulin, B Frohm, C Sala Frigerio, ...
Journal of the American Chemical Society 137 (46), 14673-14685, 2015
482015
Variance in the identification of microRNAs deregulated in Alzheimer's disease and possible role of lincRNAs in the pathology: the need of larger datasets
P Lau, CS Frigerio, B De Strooper
Ageing research reviews 17, 43-53, 2014
472014
Stem-cell-derived human microglia transplanted in mouse brain to study human disease
R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ...
Nature neuroscience 22 (12), 2111-2116, 2019
432019
PEN–2 gene mutation in a familial Alzheimer’s disease case
CS Frigerio, P Piscopo, E Calabrese, A Crestini, LM Campeggi, ...
Journal of neurology 252 (9), 1033-1036, 2005
352005
β‐Secretase cleavage is not required for generation of the intracellular C‐terminal domain of the amyloid precursor family of proteins
C Sala Frigerio, JV Fadeeva, AM Minogue, M Citron, F Van Leuven, ...
The FEBS journal 277 (6), 1503-1518, 2010
282010
γ-secretase processing of APLP1 leads to the production of a p3-like peptide that does not aggregate and is not toxic to neurons
AM Minogue, AK Stubbs, CS Frigerio, B Boland, JV Fadeeva, J Tang, ...
Brain research 1262, 89-99, 2009
282009
A self-organizing miR-132/Ctbp2 circuit regulates bimodal notch signals and glial progenitor fate choice during spinal cord maturation
E Salta, P Lau, CS Frigerio, M Coolen, L Bally-Cuif, B De Strooper
Developmental cell 30 (4), 423-436, 2014
272014
PLD3 gene and processing of APP
P Fazzari, K Horre, AM Arranz, CS Frigerio, T Saito, TC Saido, ...
Nature 541 (7638), E1-E2, 2017
252017
Nicastrin gene in familial and sporadic Alzheimer's disease
A Confaloni, L Terreni, P Piscopo, A Crestini, LM Campeggi, CS Frigerio, ...
Neuroscience letters 353 (1), 61-65, 2003
222003
Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer’s disease
WT Chen, A Lu, K Craessaerts, B Pavie, CS Frigerio, R Mancuso, X Qian, ...
BioRxiv, 719930, 2019
132019
Single-nucleus RNA-Seq is not suitable for detection of microglial activation genes in humans
N Thrupp, CS Frigerio, L Wolfs, NG Skene, N Fattorelli, S Poovathingal, ...
Cell reports 32 (13), 108189, 2020
92020
The familial British dementia mutation promotes formation of neurotoxic cystine cross-linked Amyloid Bri (ABri) oligomers
A Cantlon, CS Frigerio, DB Freir, B Boland, M Jin, DM Walsh
Journal of Biological Chemistry 290 (27), 16502-16516, 2015
92015
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