| Synthesis, Biological Evaluation, and Structure–Activity Relationships of Potent Noncovalent and Nonpeptidic Cruzain Inhibitors as Anti-Trypanosoma cruzi Agents RS Ferreira, MA Dessoy, I Pauli, ML Souza, R Krogh, AIL Sales, G Oliva, ... Journal of medicinal chemistry 57 (6), 2380-2392, 2014 | 95 | 2014 |
| Discovery of potent, reversible, and competitive cruzain inhibitors with trypanocidal activity: a structure-based drug design approach ML de Souza, C de Oliveira Rezende Junior, RS Ferreira, ... Journal of Chemical Information and Modeling 60 (2), 1028-1041, 2019 | 44 | 2019 |
| Molecular modeling and structure–activity relationships for a series of benzimidazole derivatives as cruzain inhibitors LCDADA Ivani Pauli‡, Leonardo G Ferreira‡, Mariana L de Souza, Glaucius ... FUTURE MEDICINAL CHEMISTRY 9 (8), 641-657, 2017 | 29 | 2017 |
| Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti-Trypanosoma cruzi Activity RAA Ferreira, I Pauli, TS Sampaio, ML de Souza, LLG Ferreira, ... Frontiers in chemistry 7, 798, 2019 | 25 | 2019 |
| Chemoinformatics studies on a series of imidazoles as cruzain inhibitors AR Medeiros, LLG Ferreira, ML de Souza, C de Oliveira Rezende Junior, ... Biomolecules 11 (4), 579, 2021 | 10 | 2021 |
| Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With In Vivo Activity and Favorable Pharmacokinetics I Pauli, CO Rezende Jr, BW Slafer, MA Dessoy, ML de Souza, ... Frontiers in Pharmacology 12, 774069, 2022 | 7 | 2022 |
| Characterization of Competitive Inhibitors of Plasmodium falciparum cGMP‐Dependent Protein Kinase** T Eck, M Laureano de Souza, M Delvillar, K Ashraf, ... ChemBioChem 23 (7), e202100704, 2022 | 4 | 2022 |
| Molecular targets for Chagas disease: Validation, challenges and lead compounds for widely exploited targets M Laureano de Souza, TJWJD Lapierre, gabriel Vitor de Lima Marques, ... Expert Opinion on Therapeutic Targets 27 (10), 911-925, 2023 | 3 | 2023 |
| Discovery of Imidazole-Based Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase RRY Bheemanaboina, ML De Souza, ML Gonzalez, SU Mahmood, T Eck, ... ACS Medicinal Chemistry Letters 12 (12), 1962-1967, 2021 | 3 | 2021 |
| Identificação de novos inibidores da enzima cruzaína de Trypanosoma cruzi candidatos a fármacos contra a doença de Chagas ML Souza Universidade de São Paulo, 2012 | 3 | 2012 |
| Structure–activity relationships of novel N-imidazoylpiperazines with potent anti-Trypanosoma cruzi activity RM Espinoza-Chávez, C Oliveira Rezende Júnior, ML de Souza, I Pauli, ... Future Medicinal Chemistry 16 (3), 253-269, 2024 | 1 | 2024 |
| Development of Peptoid-Based Heteroaryl-Decorated Histone Deacetylase (HDAC) Inhibitors with Dual-Stage Antiplasmodial Activity D Stopper, LP de Carvalho, ML de Souza, E Winzeler, J Held, FK Hansen | | 2024 |
| Structure–Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials JA Gilleran, K Ashraf, M Delvillar, T Eck, R Fondekar, EB Miller, ... Journal of Medicinal Chemistry, 2024 | | 2024 |
| Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase SC Xie, Y Wang, CJ Morton, RD Metcalfe, C Dogovski, CFA Pasaje, ... Nature Communications 15 (1), 937, 2024 | | 2024 |
| Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases L Wang, MJ Bohmer, J Wang, F Nardella, J Calla, M Laureano De Souza, ... Journal of Medicinal Chemistry 67 (2), 1460-1480, 2024 | | 2024 |
| QSAR and molecular docking for a series of inhibitors of the enzyme cruzain from Trypanosoma cruzi LLG Ferreira, A Medeiros, M Souza, CO Rezende Junior, RME Chávez, ... Posters, 2023 | | 2023 |
| Discovery of imidazole-based inhibitors of P. falciparum cGMP-dependent protein kinase RR Yadav Bheemanaboina, ML de Souza, ML Gonzalez, SU Mahmood, ... bioRxiv, 2021.11. 05.467463, 2021 | | 2021 |
| Discovery of novel potent, cell-permeable inhibitors of P. falciparum cGMP-dependent protein kinase RR Yadav Bheemanaboina, ML Gonzalez, SU Mahmood, T Eck, T Kreiss, ... bioRxiv, 2021.08. 24.457553, 2021 | | 2021 |
| Characterization of novel competitive inhibitors of P. falciparum cGMP-dependent protein kinase T Eck, ML de Souza, RR Yadav Bheemanaboina, R Chakrasali, T Kreiss, ... bioRxiv, 2021.06. 24.449800, 2021 | | 2021 |
| Chemoinformatics Studies on a Series of Imidazoles as Cruzain Inhibitors. Biomolecules 2021, 11, 579 AR Medeiros, LLG Ferreira, ML de Souza, C de Oliveira Rezende Junior, ... s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | | 2021 |
Adriano D. AndricopuloUniversidade de São PauloEmail confirmado em ifsc.usp.br
