Dual roles of PARP-1 promote cancer growth and progression MJ Schiewer, JF Goodwin, S Han, JC Brenner, MA Augello, JL Dean, ... Cancer discovery 2 (12), 1134-1149, 2012 | 464 | 2012 |
Androgen receptor inhibits estrogen receptor-α activity and is prognostic in breast cancer AA Peters, G Buchanan, C Ricciardelli, T Bianco-Miotto, MM Centenera, ... Cancer research 69 (15), 6131-6140, 2009 | 457 | 2009 |
Maximizing the therapeutic potential of HSP90 inhibitors LM Butler, R Ferraldeschi, HK Armstrong, MM Centenera, P Workman Molecular cancer research 13 (11), 1445-1451, 2015 | 217 | 2015 |
Minireview: the contribution of different androgen receptor domains to receptor dimerization and signaling MM Centenera, JM Harris, WD Tilley, LM Butler Molecular endocrinology 22 (11), 2373-2382, 2008 | 193 | 2008 |
Peptidomimetic targeting of critical androgen receptor–coregulator interactions in prostate cancer P Ravindranathan, TK Lee, L Yang, MM Centenera, L Butler, WD Tilley, ... Nature communications 4 (1), 1923, 2013 | 163 | 2013 |
Ex vivo culture of human prostate tissue and drug development MM Centenera, GV Raj, KE Knudsen, WD Tilley, LM Butler Nature Reviews Urology 10 (8), 483-487, 2013 | 147 | 2013 |
Evidence for Efficacy of New Hsp90 Inhibitors Revealed by Ex Vivo Culture of Human Prostate Tumors MM Centenera, JL Gillis, AR Hanson, S Jindal, RA Taylor, GP Risbridger, ... Clinical Cancer Research 18 (13), 3562-3570, 2012 | 124 | 2012 |
Targeting cell cycle and hormone receptor pathways in cancer CES Comstock, MA Augello, JF Goodwin, R De Leeuw, MJ Schiewer, ... Oncogene 32 (48), 5481-5491, 2013 | 116 | 2013 |
Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis ZD Nassar, CY Mah, J Dehairs, IJG Burvenich, S Irani, MM Centenera, ... Elife 9, e54166, 2020 | 112 | 2020 |
A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer LA Selth, R Das, SL Townley, I Coutinho, AR Hanson, MM Centenera, ... Oncogene 36 (1), 24-34, 2017 | 108 | 2017 |
A patient‐derived explant (PDE) model of hormone‐dependent cancer MM Centenera, TE Hickey, S Jindal, NK Ryan, P Ravindranathan, ... Molecular oncology 12 (9), 1608-1622, 2018 | 107 | 2018 |
Androgen control of lipid metabolism in prostate cancer: novel insights and future applications LM Butler, MM Centenera, JV Swinnen Endocrine-related cancer 23 (5), R219-R227, 2016 | 102 | 2016 |
Extracellular fatty acids are the major contributor to lipid synthesis in prostate cancer S Balaban, ZD Nassar, AY Zhang, E Hosseini-Beheshti, MM Centenera, ... Molecular Cancer Research 17 (4), 949-962, 2019 | 80 | 2019 |
Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors JL Gillis, LA Selth, MM Centenera, SL Townley, S Sun, SR Plymate, ... Oncotarget 4 (5), 691, 2013 | 69 | 2013 |
GSTP1 DNA methylation and expression status is indicative of 5-aza-2′-deoxycytidine efficacy in human prostate cancer cells K Chiam, MM Centenera, LM Butler, WD Tilley, T Bianco-Miotto PloS one 6 (9), e25634, 2011 | 62 | 2011 |
Effect of FAK inhibitor VS‐6063 (defactinib) on docetaxel efficacy in prostate cancer HM Lin, BY Lee, L Castillo, C Spielman, J Grogan, NK Yeung, JG Kench, ... The Prostate 78 (4), 308-317, 2018 | 59 | 2018 |
Hsp90: still a viable target in prostate cancer MM Centenera, AK Fitzpatrick, WD Tilley, LM Butler Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1835 (2), 211-218, 2013 | 58 | 2013 |
ELOVL5 is a critical and targetable fatty acid elongase in prostate cancer MM Centenera, JS Scott, J Machiels, ZD Nassar, DC Miller, I Zinonos, ... Cancer research 81 (7), 1704-1718, 2021 | 56 | 2021 |
Lipidomic profiling of clinical prostate cancer reveals targetable alterations in membrane lipid composition LM Butler, CY Mah, J Machiels, AD Vincent, S Irani, SM Mutuku, ... Cancer research 81 (19), 4981-4993, 2021 | 54 | 2021 |
Patient-derived models reveal impact of the tumor microenvironment on therapeutic response AA Shafi, MJ Schiewer, R de Leeuw, E Dylgjeri, PA McCue, N Shah, ... European urology oncology 1 (4), 325-337, 2018 | 45 | 2018 |