Jean-Marc Taymans
Jean-Marc Taymans
JPARC UMR837 (Inserm + Université de Lille 2)
Email confirmado em inserm.fr
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Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis
L Parisiadou, C Xie, HJ Cho, X Lin, XL Gu, CX Long, E Lobbestael, ...
Journal of Neuroscience 29 (44), 13971-13980, 2009
3232009
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation
E Greggio, I Zambrano, A Kaganovich, A Beilina, JM Taymans, V Daniëls, ...
Journal of Biological Chemistry 283 (24), 16906-16914, 2008
3202008
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
A Beilina, IN Rudenko, A Kaganovich, L Civiero, H Chau, SK Kalia, ...
Proceedings of the National Academy of Sciences 111 (7), 2626-2631, 2014
2962014
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain
JM Taymans, LH Vandenberghe, CVD Haute, I Thiry, CM Deroose, ...
Human gene therapy 18 (3), 195-206, 2007
2862007
Distribution of PINK1 and LRRK2 in rat and mouse brain
JM Taymans, C Van den Haute, V Baekelandt
Journal of neurochemistry 98 (3), 951-961, 2006
1912006
MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein
HJ Cho, G Liu, SM Jin, L Parisiadou, C Xie, J Yu, L Sun, B Ma, J Ding, ...
Human molecular genetics 22 (3), 608-620, 2013
1852013
Automated quantitative gait analysis in animal models of movement disorders
C Vandeputte, JM Taymans, C Casteels, F Coun, Y Ni, K Van Laere, ...
BMC neuroscience 11 (1), 1-11, 2010
1652010
The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites
E Greggio, JM Taymans, EY Zhen, J Ryder, R Vancraenenbroeck, ...
Biochemical and biophysical research communications 389 (3), 449-454, 2009
1642009
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant
V Daniëls, R Vancraenenbroeck, BMH Law, E Greggio, E Lobbestael, ...
Journal of neurochemistry 116 (2), 304-315, 2011
1362011
A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylation
BMH Law, VA Spain, VHL Leinster, R Chia, A Beilina, HJ Cho, ...
Journal of Biological Chemistry 289 (2), 895-908, 2014
1302014
Striatal gene expression of RGS2 and RGS4 is specifically mediated by dopamine D1 and D2 receptors: clues for RGS2 and RGS4 functions
JM Taymans, JE Leysen, X Langlois
Journal of neurochemistry 84 (5), 1118-1127, 2003
1252003
The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation
A Kumar, E Greggio, A Beilina, A Kaganovich, D Chan, JM Taymans, ...
PloS one 5 (1), e8730, 2010
1032010
Inhibition of FK506 binding proteins reduces α-synuclein aggregation and Parkinson's disease-like pathology
M Gerard, A Deleersnijder, V Daniëls, S Schreurs, S Munck, V Reumers, ...
Journal of Neuroscience 30 (7), 2454-2463, 2010
1002010
Resistance of HIV-1 reverse transcriptase against [2', 5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5 “-(4”-amino-1 “, 2”-oxathiole-2 “, 2”-dioxide)](TSAO) derivatives is …
H Jonckheere, JM Taymans, J Balzarini, S Velazquez, MJ Camarasa, ...
Journal of Biological Chemistry 269 (41), 25255-25258, 1994
1001994
LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding
JM Taymans, R Vancraenenbroeck, P Ollikainen, A Beilina, E Lobbestael, ...
PloS one 6 (8), e23207, 2011
932011
Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers
L Civiero, R Vancraenenbroeck, E Belluzzi, A Beilina, E Lobbestael, ...
PloS one 7 (8), e43472, 2012
872012
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
E Lobbestael, J Zhao, IN Rudenko, A Beylina, F Gao, J Wetter, M Beullens, ...
Biochemical Journal 456 (1), 119-128, 2013
832013
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
E Lobbestael, J Zhao, IN Rudenko, A Beylina, F Gao, J Wetter, M Beullens, ...
Biochemical Journal 456 (1), 119-128, 2013
832013
Mechanisms in dominant parkinsonism: The toxic triangle of LRRK2, α‐synuclein, and tau
JM Taymans, MR Cookson
Bioessays 32 (3), 227-235, 2010
762010
Dopamine receptor‐mediated regulation of RGS2 and RGS4 mRNA differentially depends on ascending dopamine projections and time
JM Taymans, HK Kia, R Claes, C Cruz, J Leysen, Xavier Langlois
European Journal of Neuroscience 19 (8), 2249-2260, 2004
712004
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