Next-generation approaches to understand and combat the antibiotic resistome TS Crofts, AJ Gasparrini, G Dantas Nature Reviews Microbiology 15 (7), 422-434, 2017 | 589 | 2017 |
Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome AJ Gasparrini, B Wang, X Sun, EA Kennedy, A Hernandez-Leyva, ... Nature microbiology 4 (12), 2285-2297, 2019 | 266 | 2019 |
Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance AJ Gasparrini, JL Markley, H Kumar, B Wang, L Fang, S Irum, CT Symister, ... Communications biology 3 (1), 241, 2020 | 151 | 2020 |
Antibiotic perturbation of the preterm infant gut microbiome and resistome AJ Gasparrini, TS Crofts, MK Gibson, PI Tarr, BB Warner, G Dantas Gut microbes 7 (5), 443-449, 2016 | 131 | 2016 |
Adaptive strategies of the candidate probiotic E. coli Nissle in the mammalian gut N Crook, A Ferreiro, AJ Gasparrini, MW Pesesky, MK Gibson, B Wang, ... Cell host & microbe 25 (4), 499-512. e8, 2019 | 127 | 2019 |
Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes J Park, AJ Gasparrini, MR Reck, CT Symister, JL Elliott, JP Vogel, ... Nature chemical biology 13 (7), 730-736, 2017 | 119 | 2017 |
Multiscale evolutionary dynamics of host-associated microbiomes A Ferreiro, N Crook, AJ Gasparrini, G Dantas Cell 172 (6), 1216-1227, 2018 | 117 | 2018 |
Maternal activation of the EGFR prevents translocation of gut-residing pathogenic Escherichia coli in a model of late-onset neonatal sepsis KA Knoop, PE Coughlin, AN Floyd, IM Ndao, C Hall-Moore, N Shaikh, ... Proceedings of the National Academy of Sciences 117 (14), 7941-7949, 2020 | 52 | 2020 |
Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes B Adu‐Oppong, AJ Gasparrini, G Dantas Annals of the New York Academy of Sciences 1388 (1), 42-58, 2017 | 51 | 2017 |
Semisynthetic analogues of anhydrotetracycline as inhibitors of tetracycline destructase enzymes JL Markley, L Fang, AJ Gasparrini, CT Symister, H Kumar, NH Tolia, ... ACS infectious diseases 5 (4), 618-633, 2019 | 38 | 2019 |
Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome. Nat Microbiol 4: 2285–2297 AJ Gasparrini, B Wang, X Sun, EA Kennedy, A Hernandez-Leyva, ... | 23 | 2019 |
Physiologically acceptable compositions containing microorganisms or microbial products DG Cole, J Park, SY Yang, AJ Gasparrini US Patent App. 18/009,395, 2023 | | 2023 |
Inhibition and diagnostics of emerging tetracycline resistance enzymes N Tolia, G Dantas, T Wencewicz, J Park, A Gasparrini, K Forsberg, ... US Patent 10,273,468, 2019 | | 2019 |
Semisynthetic analogues of anhydrotetracycline as potential inhibitors of tetracycline destructase enzymes J Markley, L Fang, A Gasparrini, C Symister, H Kumar, G Dantas, N Tolia, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
Mechanistic characterization of resistome and microbiome dynamics across diverse microbial habitats AJ Gasparrini Washington University in St. Louis, 2018 | | 2018 |
Identifying Potential Drivers of Differential DNA Methylation Patterns in Breast Cancer Cells A Fennoy, J Fong, J Andrews, A Gasparrini, J Edwards The FASEB Journal 29, LB143, 2015 | | 2015 |
Metagenomic signatures of early life hospitalization and antibiotic treatment in the infant gut microbiota and resistome persist long after discharge AJ Gasparrini, B Wang, X Sun, EA Kennedy, A Hernandez-Leyva, ... | | |