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Mathias Rask-Andersen
Mathias Rask-Andersen
Dept. of Neuroscience, Uppsala University
Email confirmado em neuro.uu.se
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Trends in GPCR drug discovery: new agents, targets and indications
AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam
Nature reviews Drug discovery 16 (12), 829-842, 2017
22462017
Trends in the exploitation of novel drug targets
M Rask-Andersen, MS Almén, HB Schiöth
Nature reviews Drug discovery 10 (8), 579-590, 2011
10152011
The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication
M Rask-Andersen, S Masuram, HB Schiöth
Annual review of pharmacology and toxicology 54, 9-26, 2014
3412014
Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease
T Karlsson, M Rask-Andersen, G Pan, J Höglund, C Wadelius, WE Ek, ...
Nature medicine 25 (9), 1390-1395, 2019
2102019
Advances in kinase targeting: current clinical use and clinical trials
M Rask-Andersen, J Zhang, D Fabbro, HB Schiöth
Trends in pharmacological sciences 35 (11), 604-620, 2014
2082014
Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects
M Rask-Andersen, T Karlsson, WE Ek, Å Johansson
Nature communications 10 (1), 339, 2019
2002019
Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status
M Rask-Andersen, T Karlsson, WE Ek, Å Johansson
PLoS genetics 13 (9), e1006977, 2017
1532017
Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake
M Rask-Andersen, PK Olszewski, AS Levine, HB Schiöth
Brain research reviews 62 (2), 147-164, 2010
1502010
Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers
S Voisin, MS Almén, GY Zheleznyakova, L Lundberg, S Zarei, S Castillo, ...
Genome medicine 7, 1-16, 2015
1382015
A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model?
SJ Brooks, M Rask-Andersen, C Benedict, HB Schiöth
BMC psychiatry 12, 1-11, 2012
1372012
Solute carriers as drug targets: current use, clinical trials and prospective
M Rask-Andersen, S Masuram, R Fredriksson, HB Schiöth
Molecular aspects of medicine 34 (2-3), 702-710, 2013
1102013
Epigenome-wide association study reveals differential DNA methylation in individuals with a history of myocardial infarction
M Rask-Andersen, D Martinsson, M Ahsan, S Enroth, WE Ek, ...
Human molecular genetics 25 (21), 4739-4748, 2016
892016
The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases
M Ahsan, WE Ek, M Rask-Andersen, T Karlsson, A Lind-Thomsen, ...
PLoS genetics 13 (9), e1007005, 2017
712017
Soluble ligands as drug targets
MM Attwood, J Jonsson, M Rask-Andersen, HB Schiöth
Nature Reviews Drug Discovery 19 (10), 695-710, 2020
692020
Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers
J Höglund, N Rafati, M Rask-Andersen, S Enroth, T Karlsson, WE Ek, ...
Scientific reports 9 (1), 16844, 2019
622019
Orphan drugs and their impact on pharmaceutical development
MM Attwood, M Rask-Andersen, HB Schiöth
Trends in pharmacological sciences 39 (6), 525-535, 2018
612018
Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III
GY Zheleznyakova, AV Kiselev, VG Vakharlovsky, M Rask-Andersen, ...
BMC medical genetics 12, 1-9, 2011
562011
Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children
M Sällman Almén, M Rask-Andersen, JA Jacobsson, A Ameur, I Kalnina, ...
International journal of obesity 37 (3), 424-431, 2013
492013
Tea and coffee consumption in relation to DNA methylation in four European cohorts
WE Ek, EW Tobi, M Ahsan, E Lampa, E Ponzi, SA Kyrtopoulos, ...
Human molecular genetics 26 (16), 3221-3231, 2017
462017
Differential effects of fluoxetine and venlafaxine on memory recognition: possible mechanisms of action
VP Carlini, MB Poretti, M Rask-Andersen, RA Chavan, MF Ponzio, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 38 (2), 159-167, 2012
402012
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