Bart De Strooper

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Paul SaftigProfessor of BiochemistryEmail confirmado em biochem.uni-kiel.de
Rudi D'HoogeFull professor, Biological Psychology, KU Leuven; visiting professor, VU BrusselsEmail confirmado em kuleuven.be
Patrik VerstrekenVIB Center for Brain & Disease Research & KU Leuven, Department of NeurosciencesEmail confirmado em kuleuven.vib.be
Lucía Chávez-GutiérrezUniversity of Leuven / VIB Center for Brain & Disease ResearchEmail confirmado em kuleuven.vib.be
Sébastien S HébertUniversité LavalEmail confirmado em neurosciences.ulaval.ca
Evgenia SaltaKUL/VIBEmail confirmado em cme.vib-kuleuven.be
Carlo Sala FrigerioGSKEmail confirmado em gsk.com
Iryna Benilova (Skryshevskaya)UCLEmail confirmado em cme.vib-kuleuven.be
Kris GevaertSenior Full Professor, Ghent University, BelgiumEmail confirmado em vib-ugent.be
Veerle Baekelandthoogleraar KU LeuvenEmail confirmado em kuleuven.be
sebastian munckVIB Bio Imaging Core, center for brain and disease research, VIB / KU LeuvenEmail confirmado em kuleuven.be
Aikaterini Smaragdi PapadopoulouUniversity College LondonEmail confirmado em ucl.ac.uk
Zsuzsanna Callaerts-VeghKULeuvenEmail confirmado em kuleuven.be
Rik VandenbergheUniversity of LeuvenEmail confirmado em uz.kuleuven.ac.be
Raphael KopanCincinnati Children's Hospital Medical CenterEmail confirmado em cchmc.org
Takashi SaitoNagoya City UniversityEmail confirmado em med.nagoya-cu.ac.jp
Thomas TousseynAdjunct-Kliniekhoofd Pathologische Ontleedkunde UZ Leuven; Deeltijds Hoofddocent FaculteitEmail confirmado em uzleuven.be
Adrian ListonUniversity of CambridgeEmail confirmado em cam.ac.uk
Philip ScheltensProfessor of NeurologyEmail confirmado em amsterdamumc.nl
zeger debyserKU LeuvenEmail confirmado em med.kuleuven.be

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Bart De Strooper

gewoon hoogleraar KU Leuven en onderzoeksdirecteur VIB

Email confirmado em cme.vib-kuleuven.be

Presenilin gamma-secretase regulated intramembrane proteolyis Alzheimer's Disease microRNA


Título Ordenar por citações Ordenar por ano Ordenar por título	Citado por Citado por	Ano
Alzheimer's Disease P Scheltens, K Blennow, M Breteler, B De Strooper, ... Lancet 338 (10043), 505-517, 2016	3429	2016
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain B De Strooper, W Annaert, P Cupers, P Saftig, K Craessaerts, JS Mumm, ... Nature 398 (6727), 518-522, 1999	2740	1999
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics E Karran, M Mercken, BD Strooper Nature reviews Drug discovery 10 (9), 698-712, 2011	2734	2011
Alzheimer's disease P Scheltens, B De Strooper, M Kivipelto, H Holstege, G Chételat, ... The Lancet 397 (10284), 1577-1590, 2021	2683	2021
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein B De Strooper, P Saftig, K Craessaerts, H Vanderstichele, G Guhde, ... Nature 391 (6665), 387-390, 1998	2482	1998
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes I Benilova, E Karran, B De Strooper Nature neuroscience 15 (3), 349-357, 2012	2336	2012
OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion C Frezza, S Cipolat, OM De Brito, M Micaroni, GV Beznoussenko, ... Cell 126 (1), 177-189, 2006	1851	2006
The cellular phase of Alzheimer’s disease B De Strooper, E Karran Cell 164 (4), 603-615, 2016	1784	2016
Reactive astrocyte nomenclature, definitions, and future directions C Escartin, E Galea, A Lakatos, JP O’Callaghan, GC Petzold, ... Nature neuroscience 24 (3), 312-325, 2021	1643	2021
Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons M Simons, P Keller, B De Strooper, K Beyreuther, CG Dotti, K Simons Proceedings of the National Academy of Sciences 95 (11), 6460-6464, 1998	1538	1998
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression SS Hébert, K Horré, L Nicolaï, AS Papadopoulou, W Mandemakers, ... Proceedings of the National Academy of Sciences 105 (17), 6415-6420, 2008	1399	2008
Aph-1, Pen-2, and nicastrin with presenilin generate an active γ-secretase complex B De Strooper Neuron 38 (1), 9-12, 2003	1363	2003
The secretases: enzymes with therapeutic potential in Alzheimer disease B De Strooper, R Vassar, T Golde Nature reviews neurology 6 (2), 99-107, 2010	966	2010
Control of peripheral nerve myelination by the β-secretase BACE1 M Willem, AN Garratt, B Novak, M Citron, S Kaufmann, A Rittger, ... Science 314 (5799), 664-666, 2006	922	2006
Proteolytic processing and cell biological functions of the amyloid precursor protein B De Strooper, W Annaert Journal of cell science 113 (11), 1857-1870, 2000	911	2000
The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for α-secretase activity in fibroblasts D Hartmann, B De Strooper, L Serneels, K Craessaerts, A Herreman, ... Human molecular genetics 11 (21), 2615-2624, 2002	866	2002
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling S Cipolat, T Rudka, D Hartmann, V Costa, L Serneels, K Craessaerts, ... Cell 126 (1), 163-175, 2006	858	2006
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and β-catenin translocation T Maretzky, K Reiss, A Ludwig, J Buchholz, F Scholz, E Proksch, ... Proceedings of the National Academy of Sciences 102 (26), 9182-9187, 2005	837	2005
Microglia states and nomenclature: A field at its crossroads RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ... Neuron 110 (21), 3458-3483, 2022	827	2022
Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations H Tu, O Nelson, A Bezprozvanny, Z Wang, SF Lee, YH Hao, L Serneels, ... Cell 126 (5), 981-993, 2006	793	2006

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