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Lionel tintignac
Lionel tintignac
Senior Scientist, Department of Biomedicine, Universitatspital Basel
Email confirmado em unibas.ch - Página inicial
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Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase
LA Tintignac, J Lagirand, S Batonnet, V Sirri, MP Leibovitch, ...
Journal of Biological Chemistry 280 (4), 2847-2856, 2005
5132005
Protein kinase B/Akt at a glance
E Fayard, LA Tintignac, A Baudry, BA Hemmings
Journal of cell science 118 (24), 5675-5678, 2005
4512005
Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting
LA Tintignac, HR Brenner, MA Rüegg
Physiological reviews 95 (3), 809-852, 2015
3852015
The initiation factor eIF3‐f is a major target for atrogin1/MAFbx function in skeletal muscle atrophy
J Lagirand‐Cantaloube, N Offner, A Csibi, MP Leibovitch, ...
The EMBO journal 27 (8), 1266-1276, 2008
3732008
PKB and the mitochondria: AKTing on apoptosis
A Parcellier, LA Tintignac, E Zhuravleva, BA Hemmings
Cellular signalling 20 (1), 21-30, 2008
2912008
Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy
P Castets, S Lin, N Rion, S Di Fulvio, K Romanino, M Guridi, S Frank, ...
Cell metabolism 17 (5), 731-744, 2013
2702013
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope
M Castedo, T Roumier, J Blanco, KF Ferri, J Barretina, LA Tintignac, ...
The EMBO journal 21 (15), 4070-4080, 2002
1852002
Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy
CF Bentzinger, S Lin, K Romanino, P Castets, M Guridi, S Summermatter, ...
Skeletal muscle 3, 1-16, 2013
1602013
The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse
A Csibi, K Cornille, MP Leibovitch, A Poupon, LA Tintignac, AMJ Sanchez, ...
PloS one 5 (2), e8994, 2010
1432010
MAFbx/Atrogin-1 controls the activity of the initiation factor eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal lysines
A Csibi, MP Leibovitch, K Cornille, LA Tintignac, SA Leibovitch
Journal of biological chemistry 284 (7), 4413-4421, 2009
1292009
Stabilization of MyoD by direct binding to p57Kip2
EG Reynaud, MP Leibovitch, LAJ Tintignac, K Pelpel, M Guillier, ...
Journal of Biological Chemistry 275 (25), 18767-18776, 2000
1242000
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia
DJ Ham, A Börsch, S Lin, M Thürkauf, M Weihrauch, JR Reinhard, ...
Nature communications 11 (1), 4510, 2020
1152020
Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21
M Guridi, LA Tintignac, S Lin, B Kupr, P Castets, MA Rüegg
Science signaling 8 (402), ra113-ra113, 2015
1022015
Cyclin E–Cdk2 Phosphorylation Promotes Late G1-Phase Degradation of MyoD in Muscle Cells
LA Tintignac, MP Leibovitch, M Kitzmann, A Fernandez, B Ducommun, ...
Experimental cell research 259 (1), 300-307, 2000
782000
Myostatin inactivation increases myotube size through regulation of translational initiation machinery
J Rodriguez, B Vernus, M Toubiana, E Jublanc, L Tintignac, S Leibovitch, ...
Journal of cellular biochemistry 112 (12), 3531-3542, 2011
572011
mTOR inactivation in myocardium from infant mice rapidly leads to dilated cardiomyopathy due to translation defects and p53/JNK-mediated apoptosis
L Mazelin, B Panthu, AS Nicot, E Belotti, L Tintignac, G Teixeira, Q Zhang, ...
Journal of molecular and cellular cardiology 97, 213-225, 2016
552016
Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry
LAJ Tintignac, V Sirri, MP Leibovitch, Y Lécluse, M Castedo, D Metivier, ...
Molecular and cellular biology 24 (4), 1809-1821, 2004
522004
Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia
A Börsch, DJ Ham, N Mittal, LA Tintignac, E Migliavacca, JN Feige, ...
Communications Biology 4 (1), 194, 2021
482021
Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism
M Guridi, B Kupr, K Romanino, S Lin, D Falcetta, L Tintignac, MA Rüegg
Skeletal muscle 6, 1-14, 2016
482016
SIRT3, a Mitochondrial NAD+-Dependent Deacetylase, Is Involved in the Regulation of Myoblast Differentiation
W Abdel Khalek, F Cortade, V Ollendorff, L Lapasset, L Tintignac, B Chabi, ...
PLoS One 9 (12), e114388, 2014
442014
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