Theory and modeling of asymmetric catalytic reactions Y Lam, MN Grayson, MC Holland, A Simon, KN Houk Accounts of Chemical Research 49 (4), 750-762, 2016 | 172 | 2016 |
Demystifying the asymmetry-amplifying, autocatalytic behaviour of the Soai reaction through structural, mechanistic and computational studies SV Athavale, A Simon, KN Houk, SE Denmark Nature chemistry 12 (4), 412-423, 2020 | 68 | 2020 |
P450-mediated coupling of indole fragments to forge communesin and unnatural isomers HC Lin, TC McMahon, A Patel, M Corsello, A Simon, W Xu, M Zhao, ... Journal of the American Chemical Society 138 (12), 4002-4005, 2016 | 59 | 2016 |
Catalytic enantioselective hetero-[6+ 4] and-[6+ 2] cycloadditions for the construction of condensed polycyclic pyrroles, imidazoles, and pyrazoles G Bertuzzi, MK Thøgersen, M Giardinetti, A Vidal-Albalat, A Simon, ... Journal of the American Chemical Society 141 (7), 3288-3297, 2019 | 54 | 2019 |
Arynes and cyclic alkynes as synthetic building blocks for stereodefined quaternary centers E Picazo, SM Anthony, M Giroud, A Simon, MA Miller, KN Houk, NK Garg Journal of the American Chemical Society 140 (24), 7605-7610, 2018 | 49 | 2018 |
Organocatalysis: Fundamentals and comparisons to metal and enzyme catalysis P Vogel, Y Lam, A Simon, KN Houk Catalysts 6 (9), 128, 2016 | 40 | 2016 |
Organocatalytic [6+ 4] cycloadditions via zwitterionic intermediates: Chemo-, regio-, and stereoselectivities P Yu, CQ He, A Simon, W Li, R Mose, MK Thøgersen, KA Jørgensen, ... Journal of the American Chemical Society 140 (42), 13726-13735, 2018 | 39 | 2018 |
Model for the enantioselectivity of asymmetric intramolecular alkylations by bis-quaternized cinchona alkaloid-derived catalysts CQ He, A Simon, Y Lam, APJ Brunskill, N Yasuda, J Tan, AM Hyde, ... The Journal of Organic Chemistry 82 (16), 8645-8650, 2017 | 34 | 2017 |
Inverted binding of non-natural substrates in strictosidine synthase leads to a switch of stereochemical outcome in enzyme-catalyzed pictet–spengler reactions E Eger, A Simon, M Sharma, S Yang, WB Breukelaar, G Grogan, KN Houk, ... Journal of the American Chemical Society 142 (2), 792-800, 2020 | 31 | 2020 |
Structural contributions to autocatalysis and asymmetric amplification in the Soai reaction SV Athavale, A Simon, KN Houk, SE Denmark Journal of the American Chemical Society 142 (43), 18387-18406, 2020 | 26 | 2020 |
Transition states of vicinal diamine-catalyzed aldol reactions A Simon, Y Lam, KN Houk Journal of the American Chemical Society 138 (2), 503-506, 2016 | 23 | 2016 |
On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan TE Rose, BH Curtin, KV Lawson, A Simon, KN Houk, PG Harran Chemical science 7 (7), 4158-4166, 2016 | 18 | 2016 |
Kinetic and Mechanistic Investigations to Enable a Key Suzuki Coupling for Sotorasib Manufacture─ What a Difference a Base Makes JI Murray, L Zhang, A Simon, MV Silva Elipe, CS Wei, S Caille, ... Organic Process Research & Development 27 (1), 198-205, 2022 | 10 | 2022 |
Origins of Stereoselectivity of Chiral Vicinal Diamine-Catalyzed Aldol Reactions A Simon, AJ Yeh, Y Lam, KN Houk The Journal of Organic Chemistry 81 (24), 12408-12415, 2016 | 10 | 2016 |
Acc. Chem. Res. Y Lam, MN Grayson, MC Holland, A Simon, KN Houk | 8 | 2016 |
Formal [8+ 3]-Annulation between Azaoxyallyl Cations and Tropones G Force, A Pérot, R Guillot, V Gandon, D Leboeuf Synthesis 52 (04), 553-564, 2020 | 6 | 2020 |
Origins of Stereoselectivity of Enamine–Iminium-Activated Nazarov Cyclizations by Vicinal Diamines A Simon, Y Lam, KN Houk The Journal of Organic Chemistry 82 (15), 8186-8190, 2017 | 6 | 2017 |
Demystifying the Soai reaction SV Athavale, SE Denmark | 1 | 2022 |
Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions (vol 142, pg 792 … E Eger, A Simon, M Sharma, S Yang, WB Breukelaar, G Grogan, KN Houk, ... JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 142 (9), 4525-4526, 2020 | | 2020 |
Biocatalytic sp2-sp2/sp3 CC bond formation and chiral amines W Kroutil, E Eger, J Farnberger, J Pletz, A Zadlo-Dobrowolska, G Grogan, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |