kasper Rouschop
kasper Rouschop
Universitair Docent Radiotherapie, Universiteit van Maastricht
Email confirmado em maastrichtuniversity.nl
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
autophagy 12 (1), 1-222, 2016
75592016
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the …
C Théry, KW Witwer, E Aikawa, MJ Alcaraz, JD Anderson, ...
Journal of extracellular vesicles 7 (1), 1535750, 2018
25402018
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
KMA Rouschop, T Van Den Beucken, L Dubois, H Niessen, J Bussink, ...
The Journal of clinical investigation 120 (1), 127-141, 2010
7132010
Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
JC Leemans, G Stokman, N Claessen, KM Rouschop, GJD Teske, ...
The Journal of clinical investigation 115 (10), 2894-2903, 2005
5902005
LC3/GABARAP family proteins: autophagy‐(un) related functions
MBE Schaaf, TG Keulers, MA Vooijs, KMA Rouschop
The FASEB journal 30 (12), 3961-3978, 2016
2752016
PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
KM Rouschop, LJ Dubois, TG Keulers, T van den Beucken, P Lambin, ...
Proceedings of the National Academy of Sciences 110 (12), 4622-4627, 2013
1642013
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
KMA Rouschop, CHMA Ramaekers, MBE Schaaf, TGH Keulers, ...
Radiotherapy and Oncology 92 (3), 411-416, 2009
1342009
Protection against renal ischemia reperfusion injury by CD44 disruption
KMA Rouschop, JJTH Roelofs, N Claessen, P da Costa Martins, ...
Journal of the American Society of Nephrology 16 (7), 2034-2043, 2005
1272005
Regulation of autophagy through multiple independent hypoxic signaling pathways
K Rouschop, BG Wouters
Current molecular medicine 9 (4), 417-424, 2009
1222009
Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
H Mujcic, T Rzymski, KMA Rouschop, M Koritzinsky, M Milani, AL Harris, ...
Radiotherapy and Oncology 92 (3), 450-459, 2009
1102009
CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy
KMA Rouschop, ME Sewnath, N Claessen, JJTH Roelofs, I Hoedemaeker, ...
Journal of the American Society of Nephrology 15 (3), 674-686, 2004
1102004
Level of activation of the unfolded protein response correlates with Paneth cell apoptosis in human small intestine exposed to ischemia/reperfusion
J Grootjans, CM Hodin, JJ de Haan, JPM Derikx, KMA Rouschop, ...
Gastroenterology 140 (2), 529-539. e3, 2011
1072011
Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury
JJTH Roelofs, KMA Rouschop, JC Leemans, N Claessen, AM de Boer, ...
Journal of the American society of nephrology 17 (1), 131-140, 2006
1062006
Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium
EO Pettersen, P Ebbesen, RG Gieling, KJ Williams, L Dubois, P Lambin, ...
Journal of enzyme inhibition and medicinal chemistry 30 (5), 689-721, 2015
1042015
Hypoxia induced impairment of NK cell cytotoxicity against multiple myeloma can be overcome by IL-2 activation of the NK cells
S Sarkar, WTV Germeraad, KMA Rouschop, EMP Steeghs, M van Gelder, ...
PloS one 8 (5), e64835, 2013
1042013
Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3
H Mujcic, A Nagelkerke, KMA Rouschop, S Chung, N Chaudary, PN Span, ...
Clinical Cancer Research 19 (22), 6126-6137, 2013
1032013
EGFR signaling and autophagy dependence for growth, survival, and therapy resistance
B Jutten, K Rouschop
Cell cycle 13 (1), 42-51, 2014
1012014
Small-molecule activation of p53 blocks hypoxia-inducible factor 1α and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and …
J Yang, A Ahmed, E Poon, N Perusinghe, A de Haven Brandon, G Box, ...
Molecular and cellular biology 29 (8), 2243-2253, 2009
972009
Phosphorylation of eIF2α is required for mRNA translation inhibition and survival during moderate hypoxia
M Koritzinsky, KMA Rouschop, T van den Beucken, MG Magagnin, ...
Radiotherapy and oncology 83 (3), 353-361, 2007
732007
Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response
M Wennemers, J Bussink, B Scheijen, ID Nagtegaal, ...
Breast Cancer Research 13 (4), 1-15, 2011
722011
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