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Edward Avezov
Edward Avezov
University of Cambridge, UK Dementia Research Institute
Email confirmado em cam.ac.uk - Página inicial
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Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2
J Nangalia, CE Massie, EJ Baxter, FL Nice, G Gundem, DC Wedge, ...
New England Journal of Medicine 369 (25), 2391-2405, 2013
21102013
Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated …
E Avezov, Z Frenkel, M Ehrlich, A Herscovics, GZ Lederkremer
Molecular biology of the cell 19 (1), 216-225, 2008
1682008
Endoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5–6GlcNAc2 in Glycoprotein ER-associated …
E Avezov, Z Frenkel, M Ehrlich, A Herscovics, GZ Lederkremer
Molecular biology of the cell 19 (1), 216-225, 2008
1682008
An optical technique for mapping microviscosity dynamics in cellular organelles
JE Chambers, M Kubánková, RG Huber, I López-Duarte, E Avezov, ...
Acs Nano 12 (5), 4398-4407, 2018
1332018
Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox
E Avezov, BCS Cross, GS Kaminski Schierle, M Winters, HP Harding, ...
Journal of Cell Biology 201 (2), 337-349, 2013
1032013
PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress
M Kondratyev, E Avezov, M Shenkman, B Groisman, GZ Lederkremer
Experimental cell research 313 (16), 3395-3407, 2007
892007
Single particle trajectories reveal active endoplasmic reticulum luminal flow
D Holcman, P Parutto, JE Chambers, M Fantham, LJ Young, SJ Marciniak, ...
Nature cell biology 20 (10), 1118-1125, 2018
862018
Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm
P Gulati, E Avezov, M Ma, R Antrobus, P Lehner, S O’Rahilly, GSH Yeo
Bioscience reports 34 (5), e00144, 2014
862014
Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants
S Tsunoda, E Avezov, A Zyryanova, T Konno, L Mendes-Silva, ...
Elife 3, e03421, 2014
822014
Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker
S Preissler, JE Chambers, A Crespillo-Casado, E Avezov, E Miranda, ...
Elife 4, e08961, 2015
752015
The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes
M Lu, FW van Tartwijk, JQ Lin, W Nijenhuis, P Parutto, M Fantham, ...
Science advances 6 (51), eabc7209, 2020
722020
A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins
M Shenkman, B Groisman, E Ron, E Avezov, LM Hendershot, ...
Journal of Biological Chemistry 288 (4), 2167-2178, 2013
662013
ERO1-independent production of H2O2 within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding
T Konno, E Pinho Melo, C Lopes, I Mehmeti, S Lenzen, D Ron, E Avezov
Journal of Cell Biology 211 (2), 253-259, 2015
642015
Intracellular Sources of ROS/H2O2 in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum
T Konno, EP Melo, JE Chambers, E Avezov
Cells 10 (2), 233, 2021
632021
A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation
K Kollmann, W Warsch, C Gonzalez-Arias, FL Nice, E Avezov, J Milburn, ...
Leukemia 31 (4), 934-944, 2017
602017
ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity
I Mehmeti, S Lortz, E Avezov, A Jörns, S Lenzen
Free Radical Biology and Medicine 112, 121-130, 2017
552017
TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2
EP Melo, C Lopes, P Gollwitzer, S Lortz, S Lenzen, I Mehmeti, ...
BMC biology 15, 1-15, 2017
462017
Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum
E Avezov, T Konno, A Zyryanova, W Chen, R Laine, A Crespillo-Casado, ...
BMC biology 13, 1-15, 2015
432015
A method to quantify FRET stoichiometry with phasor plot analysis and acceptor lifetime ingrowth
WY Chen, E Avezov, SC Schlachter, F Gielen, RF Laine, HP Harding, ...
Biophysical journal 108 (5), 999-1002, 2015
242015
Mechanisms regulating the secretion of the promalignancy chemokine CCL5 by breast tumor cells: CCL5's 40s loop and intracellular glycosaminoglycans
G Soria, Y Lebel-Haziv, M Ehrlich, T Meshel, A Suez, E Avezov, ...
Neoplasia 14 (1), 1-IN3, 2012
212012
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Artigos 1–20