Hugo Gutierrez-de-Teran
Hugo Gutierrez-de-Teran
Associate Professor, Cell and molecular biology, Uppsala University
Verified email at - Homepage
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Cited by
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008
M Michino, E Abola, CL Brooks, JS Dixon, J Moult, RC Stevens
Nature Reviews Drug Discovery 8 (6), 455-463, 2009
Advances in GPCR Modeling Evaluated by the GPCR Dock 2013 Assessment: Meeting New Challenges
I Kufareva, V Katritch, PGD 2013, RC Stevens, R Abagyan
Structure 22, 1120, 2014
The role of a sodium ion binding site in the allosteric modulation of the A2A adenosine G protein-coupled receptor
H Gutiérrez-de-Terán, A Massink, D Rodríguez, W Liu, GW Han, ...
Structure 21 (12), 2175-2185, 2013
Crystal structure of thioflavin-T and its binding to amyloid fibrils: insights at the molecular level
C Rodríguez-Rodríguez, A Rimola, L Rodríguez-Santiago, P Ugliengo, ...
Chemical Communications 46 (7), 1156-1158, 2010
Linear Interaction Energy: Method and Applications in Drug Design
H Gutiérrez-de-Terán, J Åqvist
Methods in Molecular Biology - Computational Drug Discovery and Design 819 …, 2012
Molecular dynamics simulations reveal insights into key structural elements of adenosine receptors
D Rodríguez, A Piñeiro, H Gutiérrez-de-Terán
Biochemistry 50 (19), 4194-4208, 2011
Sodium ion binding pocket mutations and adenosine A2A receptor function
A Massink, H Gutiérrez-de-Terán, EB Lenselink, NVO Zacarías, L Xia, ...
Molecular pharmacology 87 (2), 305-313, 2015
A C-terminal mutation of ATP1A3 underscores the crucial role of sodium affinity in the pathophysiology of rapid-onset dystonia-parkinsonism
P Blanco-Arias, AP Einholm, H Mamsa, C Concheiro, ...
Human molecular genetics 18 (13), 2370-2377, 2009
Computational inhibitor design against malaria plasmepsins
S Bjelic, M Nervall, H Gutiérrez-de-Terán, K Ersmark, A Hallberg, J Åqvist
Cellular and Molecular Life Sciences 64 (17), 2285-2305, 2007
Computational prediction of alanine scanning and ligand binding energetics in G-protein coupled receptors
L Boukharta, H Gutiérrez-de-Terán, J Åqvist
PLoS Comput Biol 10 (4), e1003585, 2014
Pyrimidine Derivatives as Potent and Selective A3 Adenosine Receptor Antagonists
V Yaziji, D Rodríguez, H Gutiérrez-de-Terán, A Coelho, O Caamano, ...
Journal of medicinal chemistry 54 (2), 457-471, 2011
Ligand-, structure-and pharmacophore-based molecular fingerprints: a case study on adenosine A 1, A 2A, A 2B, and A 3 receptor antagonists
F Sirci, L Goracci, D Rodríguez, J van Muijlwijk-Koezen, ...
Journal of computer-aided molecular design 26 (11), 1247-1266, 2012
Discovery of 3, 4-Dihydropyrimidin-2 (1 H)-ones As a Novel Class of Potent and Selective A2B Adenosine Receptor Antagonists
A Crespo, A El Maatougui, P Biagini, J Azuaje, A Coelho, J Brea, MI Loza, ...
ACS Medicinal Chemistry Letters 4 (11), 1031-1036, 2013
Structural and energetic effects of A 2A adenosine receptor mutations on agonist and antagonist binding
H Keränen, H Gutiérrez-de-Terán, J Åqvist
PloS one 9 (10), e108492, 2014
Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV
K Ersmark, M Nervall, H Gutiérrez-de-Terán, E Hamelink, LK Janka, ...
Bioorganic & medicinal chemistry 14 (7), 2197-2208, 2006
GPCR-ModSim: A comprehensive web based solution for modeling G-protein coupled receptors
M Esguerra, A Siretskiy, X Bello, J Sallander, H Gutiérrez-de-Terán
Nucleic Acids Research 44 (W1), W455-62, 2016
Structural mapping of adenosine receptor mutations: ligand binding and signaling mechanisms
W Jespers, AC Schiedel, LH Heitman, RM Cooke, L Kleene, ...
Trends in pharmacological sciences 39 (1), 75-89, 2018
Characterization of the dynamic events of GPCRs by automated computational simulations
H Gutiérrez-de-Terán, X Bello, D Rodríguez
Biochemical Society Transactions 41 (1), 205-212, 2013
Molecular modelling of G protein‐coupled receptors through the web
D Rodríguez, X Bello, H Gutiérrez‐de‐Terán
Molecular Informatics 31 (5), 334-341, 2012
α-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteases
KM Orrling, MR Marzahn, H Gutiérrez-de-Terán, J Åqvist, BM Dunn, ...
Bioorganic & medicinal chemistry 17 (16), 5933-5949, 2009
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