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Rita Perfeito
Rita Perfeito
Center for Neuroscience and Cell Biology; Center for Innovative Medicine and Biotechnology
Verified email at uc.pt
Title
Cited by
Cited by
Year
Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases
D Rufino-Ramos, PR Albuquerque, V Carmona, R Perfeito, RJ Nobre, ...
Journal of Controlled Release 262, 247-258, 2017
3552017
Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse
R Perfeito, T Cunha-Oliveira, AC Rego
Free Radical Biology and Medicine 53 (9), 1791-1806, 2012
1332012
Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells.
R Perfeito, D Lázaro, T Outeiro, AC Rego
Molecular and Cellular Neurosicences 62, 51-9, 2014
1102014
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality
J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ...
Stem cell reports 12 (5), 878-889, 2019
852019
Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse
R Perfeito, T Cunha-Oliveira, AC Rego
Free Radical Biology and Medicine 62, 186-201, 2013
812013
Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells
R Perfeito, M Ribeiro, AC Rego
Archives of toxicology 91, 1245-1259, 2017
422017
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1
J Walter, S Bolognin, SK Poovathingal, S Magni, D Gerard, PMA Antony, ...
Cell Reports 37 (3), 2021
242021
Trolox protection of myelin membrane in hydrogen peroxide-treated mature oligodendrocytes
R Perfeito, J Pereira, CR Oliveira, J Bettencourt-Relvas, A Cristina Rego
Free radical research 41 (4), 444-451, 2007
222007
Papel da alfa-sinucleína e da disfunção mitocondrial associada à doença de Parkinson
R Perfeito, AC Rego
Revista Neurociências 20 (2), 273-284, 2012
212012
Stem cell-based therapies for polyglutamine diseases
LS Mendonça, I Onofre, CO Miranda, R Perfeito, C Nóbrega, ...
Polyglutamine Disorders, 439-466, 2018
152018
Expanded and wild-type Ataxin-3 modify the redox status of SH-SY5Y cells overexpressing α-synuclein
C Noronha, R Perfeito, M Laço, U Wüllner, AC Rego
Neurochemical research 42, 1430-1437, 2017
92017
Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3
D Rufino-Ramos, PR Albuquerque, K Leandro, V Carmona, IM Martins, ...
Molecular Therapy 31 (5), 1275-1292, 2023
82023
Interplay between alpha-synuclein and oxidative stress in Parkinson’s disease cell models
R Perfeito
Universidade de Coimbra, 2012
12012
Post-translational modifications of alpha-synuclein and mitochondrial dysfunction in Parkinson’s disease
R Perfeito, AC Rego
Outeiro. T., ed.) Transworld Research Network, 203-230, 2008
12008
Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease (MJD)/Spinocerebellar Ataxia type-3 (SCA3)
D Rufino-Ramos, K Leandro, P Albuquerque, V Carmona, I Martins, ...
HUMAN GENE THERAPY 33 (23-24), A178-A178, 2022
2022
Systemic delivery of the brain-targeting AAV-PHPeB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of Machado-Joseph disease: a promising therapeutic strategy
B Serra, SP Duarte, N Cartier, S Alves, LP de Almeida, R Perfeito
HUMAN GENE THERAPY 33 (23-24), A85-A85, 2022
2022
Extracellular vesicles for therapy of spinocerebellar ataxia type 3
D Rufino-Ramos, V Carmona, IM Martins, M Barreira, PR Albuquerque, ...
HUMAN GENE THERAPY 30 (11), A101-A101, 2019
2019
Intersection of autophagy and exosome secretion on alpha-synuclein spreading pattern in in vitro models of Parkinson's disease
R Perfeito, V Anjos, RJ Nobre, M Garrido, J Schwamborn, LP de Almeida
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 49, 87-88, 2019
2019
Optimization of a size-exclusion chromatography protocol to isolate plasma-derived extracellular vesicles for transcriptional biomarkers research
L Gaspar, MM Santana, R Perfeito, P Albuquerque, TM Ribeiro-Rodrigues, ...
Journal of Extracellular Vesicles 7, 151-152, 2018
2018
Autophagy activation prevents alpha-synuclein secretion in exosomes
R Perfeito, V Anjos, RJ Nobre, M Garrido, LP de Almeida
Journal of Extracellular Vesicles 5, PT6.01, 2016
2016
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